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Table 1 Chromosome deficiency lines that depress the viability of SMN7Ao heterozygotes

From: Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

Chromosome

Deficiency

Deleted region

Deleted genes

% Flies eclosed mean ± SEM

Previously identified modifiersa

Interaction strength

2L

Df(2L)BSC37

22D1–22F2

74

84.1 ± 0.5

tho2

+

2L

Df(2L)ed1

24A2–24D4

66

76.7 ± 6.3

+

2L

Df(2L)BSC5

26B1–26D2

79

79.9 ± 5.4

eIF4A

+

2L

Df(2L)cact-255rv64

35F6–36D

181

83.1 ± 1.7

VhaSFD, Tpr2, Sytα

+

3L

Df(3L)HR119

63C6–63F7

75

81.5 ± 7.8

enc, PIG-C, CG12016, PIG-B, CG32262, CG32263, CG32264, Rdh, CG42456

+

3L

Df(3L)h-i22

66D10–66E2

29

66 ± 6.7

++

3L

Df(3L)vin5

68A2–69A1

239

71.1 ± 1.4

Sod1, CG14130, Alg10, NaPi-III

++

3L

Df(3L)81k19

73A3–74F4

175

0

SMN

++++

3R

Df(3R)WIN11

83E1–84A5

107

70.3 ± 8.7

Dmtn

++

3R

Df(3R)T-32

86D9–87C4

241

59.4 ± 7.2

svp, GstD3, Cyp313a2, Jupiter, Csk

+++

3R

Df(3R)BSC43

92F7–93B6

54

81.4 ± 3

Syp, CG17272

+

3R

Df(3R)B81

99D3–3Rt

280

48 ± 0.6

heph, aralar1, CG9682, mRpL32, CG1750

++++

  1. aGenetic modifiers previously identified in the Chang et al. [7] and Sen et al. [10] studies