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Table 1 Chromosome deficiency lines that depress the viability of SMN7Ao heterozygotes

From: Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

Chromosome Deficiency Deleted region Deleted genes % Flies eclosed mean ± SEM Previously identified modifiersa Interaction strength
2L Df(2L)BSC37 22D1–22F2 74 84.1 ± 0.5 tho2 +
2L Df(2L)ed1 24A2–24D4 66 76.7 ± 6.3 +
2L Df(2L)BSC5 26B1–26D2 79 79.9 ± 5.4 eIF4A +
2L Df(2L)cact-255rv64 35F6–36D 181 83.1 ± 1.7 VhaSFD, Tpr2, Sytα +
3L Df(3L)HR119 63C6–63F7 75 81.5 ± 7.8 enc, PIG-C, CG12016, PIG-B, CG32262, CG32263, CG32264, Rdh, CG42456 +
3L Df(3L)h-i22 66D10–66E2 29 66 ± 6.7 ++
3L Df(3L)vin5 68A2–69A1 239 71.1 ± 1.4 Sod1, CG14130, Alg10, NaPi-III ++
3L Df(3L)81k19 73A3–74F4 175 0 SMN ++++
3R Df(3R)WIN11 83E1–84A5 107 70.3 ± 8.7 Dmtn ++
3R Df(3R)T-32 86D9–87C4 241 59.4 ± 7.2 svp, GstD3, Cyp313a2, Jupiter, Csk +++
3R Df(3R)BSC43 92F7–93B6 54 81.4 ± 3 Syp, CG17272 +
3R Df(3R)B81 99D3–3Rt 280 48 ± 0.6 heph, aralar1, CG9682, mRpL32, CG1750 ++++
  1. aGenetic modifiers previously identified in the Chang et al. [7] and Sen et al. [10] studies