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Table 3 Clinical outcomes of 70 pneumococcal pneumonia cases diagnosed based on clinical judgment at admission

From: The efficacy of high-dose penicillin G for pneumococcal pneumonia diagnosed based on initial comprehensive assessment at admission: an observational study

Characteristics Number of patients (% [95% CI])
Total, N = 70
Primary outcome
 Clinical success until day 6a 61 (87.1 [79.1 to 95.2])
Secondary outcomes
 Adverse drug events due to penicillin G 0 (0.0 [0.0 to 0.0])
 Switch to other antibioticsb 4 (5.7 [0.1 to 11.3])b
 30-day mortality 1 (1.4 [− 1.4 to 4.3])c
 In-hospital death 2 (2.9 [− 1.1 to 6.9])c, d
 Readmission within 30 days 1 (1.4 [− 1.4 to 4.3])
  1. aClinical success was defined as the condition in which all the following threshold values were achieved for a 24-h period: temperature, ≤ 37.2 °C; heart rate, ≤ 100 beats/min; respiratory rate, ≤ 24 breaths/min; systolic blood pressure, ≥ 90 mmHg; oxygen saturation, ≥ 90% or arterial oxygen partial pressure, and ≥ 60 mmHg when the patient was not receiving supplemental oxygen
  2. bThis value includes cases in which penicillin G was replaced by other antibiotics because of pneumonia treatment failure (more detailed information was described in an Additional file 2)
  3. cThis patient died due to hospital-acquired pneumonia after recovery from community- acquired pneumonia
  4. dThis patient died due to the complication of acute respiratory distress syndrome in influenza A pneumonia derived from an in-hospital influenza outbreak