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Fig. 3 | BMC Research Notes

Fig. 3

From: Dynamic bimodal changes in CpG and non-CpG methylation genome-wide upon CGGBP1 loss-of-function

Fig. 3

CGGBP1 regulates methylation at TSSs of the cytosine methylation regulatory genes. Cytosine methylation levels in 1 kb flank from TSSs of various transcripts the cytosine methylation regulatory genes (DNMT1, DNMT3A, TET2, AICDA, TDG, NEIL1, MBD4, APOBEC3H and APOBEC3G) was plotted for both the samples S1 and S2 and for both the strands (top and bottom). The cluster of cytosines exhibiting methylation change is highlighted by boxes with dashed lines. For each gene, direction of transcription is marked by arrowheads along-with ENSEMBL transcript ID. All transcripts in the regions are not shown as in Additional file 1: Fig. S7. Plots were generated using deepTools [8] and compiled in Keynote (Apple)

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