Differential expression of cytokines and receptor expression during anoxic growth

BMC Research Notes

Table 1 Effect of anoxic culture on expression of pro- and anti-inflammatory cytokines in the presence (day 3) and absence (day 10) of HIF1 expression

Cytokines	Relative change (anoxic/normoxic)^a Day 3^b	Relative change (anoxic/normoxic)^a Day 10^b
IFN-α2	0.7^{c d}	0.9
GRO	1.1^{c d}	1.3^c
IL-6	0.9^d	1.9^c
IL-8	1.9^{c d}	3.4^c
CXCL-10	0.7^{c d}	0.9
CXCL-9	1.0^d	1.1^c
G-CSF	1.3^{c d}	1.2^c
IL-11	1.4^{c d}	1.1^c

^aRatio anoxic cytokine levels to normoxic levels
^bNumber of days in the absence of oxygen
^cSignificant change in production (p ≤ 0.01). n = 19 replicates
^dSignificant change (p ≤ 0.01) between day 3 and day 10 relative cytokine production

ISSN: 1756-0500