Table 1 Summarization of demographic and clinico-pathological features of patients with HCC and those with hepatitis
Clinico-biological features | HCC n = 80 | Hepatitis n = 247 | P values |
|---|---|---|---|
Age (mean ± SD) | 38.1 ± 15.2 | 35.6 ± 12.5 | 0.21 (ns) |
Sex ratio M:F | 1.9 (52/28) | 2.04 (166/81) | ns |
Risk factors (%) | |||
HBV | 52.5% | 5.8% | 0.008 |
HCV | 36.5% | 38.0% | ns |
Unknown risk | 11.2% | 56.2% | 3.07E−5 |
Steatosis (%) | |||
Total | 60.0 | 5.9 | |
HBV | 23.5 | 1.2 | |
HCV | 75.5 | 4.7 | |
Unknown risk | 1.01 | 00 | na |
Morphology | |||
Microtrabecular | 42.6 | – | |
Macrotrabecular | 13.7 | – | na |
Acinar-pseudoglandular | 32.5 | – | |
Scirrhous | 11.2 | – | |
Fibrosis | n = 73 | n = 210 | |
F0 | 5.4 | 9.5 | |
F1 | 9.5 | 52.8 | |
F2 | 38.3 | 28.5 | 0.0321 |
F3 | 24.6 | 5.7 | 8.8 E−14 |
F4 | 20.5 | 3.3 | 3.9 E−6 |
Necro-inflammation | n = 74 | n = 237 | |
A0 | 2.7 | 3.3 | |
A1 | 33.8 | 37.1 | ns |
A2 | 41.9 | 45.9 | ns |
A3 | 20.2 | 13.5 | 0.0334 |
Cellular variant | |||
Clear cells | 12.5 | 24.9 | 0.0279 |
Ballooning degeneration | 3.7 | 25.9 | 4.3 E−6 |