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Table 1 Summarization of demographic and clinico-pathological features of patients with HCC and those with hepatitis

From: Dichotomous associations of liver pathology with hepatocellular carcinoma morphology in Middle Africa: the situation in Cameroon

Clinico-biological features HCC n = 80 Hepatitis n = 247 P values
Age (mean ± SD) 38.1 ± 15.2 35.6 ± 12.5 0.21 (ns)
Sex ratio M:F 1.9 (52/28) 2.04 (166/81) ns
Risk factors (%)
 HBV 52.5% 5.8% 0.008
 HCV 36.5% 38.0% ns
 Unknown risk 11.2% 56.2% 3.07E−5
Steatosis (%)
 Total 60.0 5.9  
 HBV 23.5 1.2  
 HCV 75.5 4.7  
 Unknown risk 1.01 00 na
Morphology
 Microtrabecular 42.6  
 Macrotrabecular 13.7 na
 Acinar-pseudoglandular 32.5  
 Scirrhous 11.2  
Fibrosis n = 73 n = 210  
 F0 5.4 9.5  
 F1 9.5 52.8  
 F2 38.3 28.5 0.0321
 F3 24.6 5.7 8.8 E−14
 F4 20.5 3.3 3.9 E−6
Necro-inflammation n = 74 n = 237  
 A0 2.7 3.3  
 A1 33.8 37.1 ns
 A2 41.9 45.9 ns
 A3 20.2 13.5 0.0334
Cellular variant
 Clear cells 12.5 24.9 0.0279
 Ballooning degeneration 3.7 25.9 4.3 E−6
  1. HCC hepatocellular carcinoma, HBV hepatitis B virus, HCV hepatitis C virus, F0 no fibrosis, F1 portal fibrosis without septa, F2 portal fibrosis and few septa, F3 numerous septa without cirrhosis, F4 cirrhosis, A0 none, A1 mild, A2 moderate, et A3 severe, M male, F female, ns not significant, na not available