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Fig. 3 | BMC Research Notes

Fig. 3

From: Intranasal administration of cationic liposomes enhanced granulocyte–macrophage colony-stimulating factor expression and this expression is dispensable for mucosal adjuvant activity

Fig. 3

Effect of anti-GM-CSF neutralizing antibodies on ovalbumin (OVA)-specific antibody responses induced by DOTAP/DC-chol liposomes. Mice were pre-treated intraperitoneally with anti-GM-CSF neutralizing antibody (100 µg/mouse) at day 0 and then immunized intranasally with PBS, OVA alone, or OVA plus DOTAP/DC-chol liposomes on days 2 and 9. Nasal washes and sera were collected on day 16. OVA-specific nasal IgA and serum IgGs were detected using ELISA. The data were obtained from three independent experiments. NS not significant as evaluated using the Kruskal–Wallis test with Dunn’s post hoc test

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