Table 1 The overlap between the identified PPP1R3F regulons from both datasets (n = 177 genes) and several candidate gene lists of ASDs and ID (intellectual disability)
Source of gene list | # Genes in the gene list | Overlap | P value | Fold enrichment | References |
|---|---|---|---|---|---|
SFARI gene list (v 2.0) | 881 | 17 | 0.0008 | 2.4 | [37] |
Intellectual disability database, University of Colorado Denver | 1095 | 11 | 0.268 | 1.2 | [41] |
Intellectual disability database, University of Chicago | 1969 | 22 | 0.072 | 1.4 | [38] |
Intellectual disabilities (IDS v. 1.0) | 897 | 11 | 0.097 | 1.5 | [42] |
ASD de novo mutation list (v. 1.5)a | 1248 | 11 | 0.124 | 1.1 | [43] |