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Table 1 The overlap between the identified PPP1R3F regulons from both datasets (n = 177 genes) and several candidate gene lists of ASDs and ID (intellectual disability)

From: Transcriptional network analysis on brains reveals a potential regulatory role of PPP1R3F in autism spectrum disorders

Source of gene list # Genes in the gene list Overlap P value Fold enrichment References
SFARI gene list (v 2.0) 881 17 0.0008 2.4 [37]
Intellectual disability database, University of Colorado Denver 1095 11 0.268 1.2 [41]
Intellectual disability database, University of Chicago 1969 22 0.072 1.4 [38]
Intellectual disabilities (IDS v. 1.0) 897 11 0.097 1.5 [42]
ASD de novo mutation list (v. 1.5)a 1248 11 0.124 1.1 [43]
  1. P values are calculated by two-sided Fisher’s exact test
  2. aWe have removed de novo mutations in intergenic and intronic regions