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Table 1 Association of clinico-pathologic parameters of metaplastic breast cancer subtype with Ductal carcinoma, NOS

From: Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast

  n (%) P-value
Metaplastic Ductal, NOS Total
Age (years)ab 49.21 ± 12.92 50.54 ± 12.48 0.49
Age group (n = 1738)
 ≤ 30 3 (3.3) 89 (5.3) 92 (5.3) 0.767
 31–50 21 (48.8) 822 (48.8) 843 (48.5)
 51–70 16 (37.2) 692 (40.8) 708 (40.7)
 > 70 3 (7) 92 (5.4) 95 (5.5)
Tumor grade (n = 1738)
 Grade 1 3 (7) 160 (9.4) 163 (9.4) ≤ 0.05
 Grade 2 5 (11.6) 945 (55.8) 950 (54.7)
 Grade 3 35 (81.4) 590 (34.8) 625 (36)
Ki67 valueab 40.05 ± 22.67 35.92 ± 23.33 0.252
Ki67 index category (n = 1738)
 < 15 4 (9.3) 373 (22) 377 (21.7) 0.203
 15–24 11 (25.6) 311 (18.3) 322 (18.5)
 25–44 12 (27.9) 406 (24) 418 (24.1)
 > 44 16 (37.2) 605 (35.7) 621 (35.7)
Size of tumorab 36.77 ± 15.31 36.11 ± 14.84 0.825
Tumor stage (n = 660)
 T1 4 (15.4) 83 (13.1) 87 (13.2) 0.695
 T2 17 (65.4) 454 (71.6) 471 (71.4)
 T3 5 (19.2) 97 (15.3) 102 (15.5)
Nodal status (n = 660)
 Positive 12 (46.2) 318 (50.2) 330 (50) 0.689
 Negative 14 (53.8) 316 (48.8) 330 (50)
N stage (n = 660)
 N0 14 (53.8) 320 (50.5) 334 (50.6) 0.431
 N1 5 (19.2) 130 (20.5) 135 (20.5)
 N2 1 (3.8) 85 (13.4) 86 (13)
 N3 6 (23.1) 99 (15.6) 105 (15.9)
Laterality (n = 1738)
 Left 19 (44.2) 865 (51) 884 (50.9) 0.375
 Right 24 (55.8) 830 (49) 854 (49.1)
ER (n = 1738)
 Positive 9 (20.9) 1019 (60.1) 1028 (59.1) ≤ 0.05
 Negative 34 (79.1) 676 (39.9) 710 (40.9)
PR (n = 1738)
 Positive 6 (14) 779 (46) 785 (45.2) ≤ 0.05
 Negative 37 (86) 916 (54) 953 (54.8)
Her2neu (n = 1738)
 Positive 9 (20.9) 742 (43.8) 751 (43.2) ≤ 0.05
 Negative 34 (79.1) 953 (56.2) 987 (56.8)
Lymphocytic infiltration (n = 660)
 Absent 10 (38.5) 364 (57.4) 374 (56.7) 0.132
 Moderate 13 (50) 210 (33.1) 223 (33.8)
 Severe 3 (11.5) 60 (9.5) 63 (9.5)
Insitu component (n = 659)
 Present 11 (42.3) 432 (68.2) 443 (67.2) ≤ 0.05
 Absent 15 (57.7) 201 (31.8) 216 (32.8)
Lymphovascular invasion (n = 660)
 Present 8 (30.8) 157 (24.8) 165 (25) 0.488
 Absent 18 (69.2) 477 (75.2) 495 (75)
Dermal lymphatic invasion (n = 660)
 Present 0 (0) 78 (12.3) 78 (11.8) 0.061
 Absent 26 (100) 556 (87.7) 582 (88.2)
Pagetoid spread (n = 660)
 Present 0 (0) 14 (2.2) 14 (2.1) 1.000
 Absent 26 (100) 620 (97.8) 646 (97.9)
Molecular subtypes(n = 1738)
 Triple negative 29 (67.4) 298 (17.6) 327 (18.8) ≤ 0.05
 HER 2 5 (11.6) 363 (21.4) 368 (21.2)
 Luminal A 1 (2.3) 287 (16.9) 288 (16.6)
 Luminal B 8 (18.6) 747 (44.1) 755 (43.4)
  1. Chi Square applied
  2. aMean ± SD
  3. bIndependent t-Test