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Table 2 Association of clinico-pathologic parameters of micropapillary breast cancer subtype with ductal carcinoma, NOS

From: Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast

  n (%) P-value
Micropapillary Ductal, NOS Total
Age (years)ab 48.20 ± 14.02 50.54 ± 12.48 0.47
Age group (n = 1710)
 ≤ 30 2 (13.3) 89 (5.3) 91 (5.3) 0.323
 31–50 7 (46.7) 822 (48.5) 829 (48.5)
 51–70 5 (33.3) 692 (40.8) 697 (40.8)
 > 70 1 (6.7) 92 (5.4) 93 (5.4)
Tumor grade (n = 1710)
 Grade 1 0 (0) 160 (9.4) 160 (9.4) 0.386
 Grade 2 11 (73.3) 945 (55.8) 956 (55.9)
 Grade 3 4 (26.7) 590 (34.8) 594 (34.7)
Ki67 valueab 35.80 ± 22.94 35.92 ± 23.33 0.984
Ki67 index category (n = 1710)
 < 15 2 (13.3) 373 (22) 375 (21.9) 0.582
 15–24 4 (26.7) 311 (18.3) 315 (18.4)
 25–44 5 (33.3) 406 (24) 411 (24)
 > 44 4 (26.7) 605 (35.7) 609 (35.6)
Size of tumorab 33.11 ± 14.77 36.11 ± 14.84 0.547
Tumor stage (n = 643)
 T1 1 (11.1) 83 (13.1) 84 (13.1) 1.000
 T2 7 (77.8) 454 (71.6) 461 (71.7)
 T3 1 (11.1) 97 (15.3) 98 (15.2)
Nodal status (n = 643)
 Positive 6 (66.7) 318 (50.2) 324 (50.4) 0.505
 Negative 3 (33.3) 316 (49.8) 319 (49.6)
N stage (n = 643)
 N0 4 (44.4) 320 (50.5) 324 (50.4) 0.417
 N1 2 (22.2) 130 (20.5) 132 (20.5)
 N2 0 (0) 85 (13.4) 85 (13.2)
 N3 3 (33.3) 99 (15.6) 102 (15.9)
Laterality (n = 1710)
 Left 9 (60) 865 (51) 874 (51.1) 0.489
 Right 6 (40) 830 (49) 836 (48.9)
ER (n = 1710)
 Positive 13 (86.7) 1019 (60.1) 1032 (60.4) ≤ 0.05
 Negative 2 (13.3) 676 (39.9) 678 (39.6)
PR (n = 1710)
 Positive 11 (73.3) 779 (46) 790 (46.2) ≤ 0.05
 Negative 4 (26.7) 916 (54) 920 (53.8)
Her2neu (n = 1710)
 Positive 9 (60) 742 (43.8) 751 (43.9) 0.207
 Negative 6 (40) 953 (56.2) 959 (56.1)
Lymphocytic infiltration (n = 643)
 Absent 3 (33.3) 364 (57.4) 367 (57.1) 0.241
 Moderate 5 (55.6) 210 (33.1) 215 (33.4)
 Severe 1 (9.5) 60 (9.5) 61 (9.5)
Insitu component (n = 642)
 Present 2 (22.2) 432 (68.2) 434 (67.6) ≤ 0.05
 Absent 7 (77.8) 201 (31.8) 208 (32.4)
Lymphovascular invasion (n = 643)
 Present 7 (77.8) 157 (24.8) 164 (25.5) ≤ 0.05
 Absent 2 (22.2) 477 (75.2) 479 (74.5)
Dermal lymphatic invasion (n = 643)
 Present 2 (2.5) 78 (12.3) 80 (12.4) 0.311
 Absent 7 (77.8) 556 (87.7) 563 (87.6)
Pagetoid spread (n = 643)
 Present 0 (0) 14 (2.2) 14 (2.2) 1.000
 Absent 9 (100) 620 (97.8) 629 (97.8)
Molecular subtypes (n = 1710)
 Triple negative 1 (6.7) 298 (17.6) 299 (17.5) ≤ 0.05
 HER 2 1 (6.7) 363 (21.4) 364 (21.3)
 Luminal A 0 (0) 287 (16.9) 287 (16.8))
 Luminal B 13 (86.7) 747 (44.1) 760 (44.4)
  1. Chi Square applied
  2. aMean ± SD
  3. bIndependent t-Test