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Table 3 Immunophenotyping of spleen (median/IQR)

From: Tumor growth activity of duloxetine in Ehrlich carcinoma in mice

  D5 D30 S p
CD3 (× 107/mL)a 1.0 (0.7–1.4)* 1.3 (1.1–1.6)* 2.2 (1.2–2.4) 0.045
CD4 (× 107/mL)a 0.7 (0.5–0.9) 0.8 (0.6–0.9) 1.5 (1.0–1.7) 0.2448
CD8 (× 107/mL)a 0.2 (0.1–0.2) 0.3 (0.2–0.5) 0.4 (0.2–0.5) 0.088
CD28 (× 105/mL)b 39 (37–40)* 42 (39–45)* 51 (45–52) 0.010
  1. D5 5 mg/kg, D30 duloxetine 30 mg/kg, S saline
  2. aAbsolute frequency of spleen lymphocytes
  3. bFluorescence intensity of spleen lymphocytes; Kruskal–Wallis test; IQR interquartile
  4. *Significant