Fig. 3

CNV concordance across cell culture expansions. This figure displays boxplots of the distribution of pairwise shared CNV regions between DNA (from blood) and cell culture for each individual subject. Shared CNV regions for the initial transformed cell culture and three expansions cultures are shown along the X-axis. The Y-axis displays the percentage of CNV regions that were estimated to be shared using PennCNV calls [11]. Red dash lines indicate the minimum and maximum number of shared CNVs across technical replicates. a Displays results for all CNV regions, and b displays results that exclude the three immunoglobulin regions identified in the samples