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Table 1 FOXP3, NOTCH1 and HES1 mRNA expression in FOXP3 silenced T-ALL cells

From: FOXP3 knockdown inhibits the proliferation and reduces NOTCH1 expression of T cell acute lymphoblastic leukemia cells

  Jurkat KOPT-K1
FOXP3 28.6 ± 3.2%* 44.5 ± 18.7%*
NOTCH1 55.5 ± 3.7%* 59.9 ± 9.3%*
HES1 52.0 ± 18.7%* 34.0 ± 11.3%*
  1. RNA was extracted from Jurkat or KOPT-K1 cells transfected with control siRNA or FOXP3 siRNA (HSS121458) after 4 h. The expression of FOXP3, NOTCH1 and HES1 was measured by qPCR and normalized to that of ACTB. The values indicate the expression in FOXP3 silenced cells relative to that in control cells as the mean ± standard error of the mean (n = 3)
  2. * P < 0.05 compared to the gene expression in control cells