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Table 2 Clinical signs and symptoms of typhoid fever and their association with blood culture positivity among adult patients visiting Shashemene Referral Hospital, southern Ethiopia, 2016

From: Typhoid fever: clinical presentation and associated factors in febrile patients visiting Shashemene Referral Hospital, southern Ethiopia

Variable (n = 421)

Total N (%)

Culture pos N (%)

COR (95% CI)

AOR (95% CI)

P-value

Fatigue

 Yes

348 (82.7)

17 (4.9)

1.1 (0.37–3.46)

  

 No

73 (17.3)

4 (5.5)

1

  

Fever

 < 5 days

358 (85.0)

6 (1.7)

1

1

 

 ≥ 5 days

63 (15.0)

15 (23.8)

18.3 (6.78–49.5)*

18.2 (6.45–54.5)

0.001

Loss of appetite

 Yes

273 (64.8)

13 (4.8)

1

  

 No

148 (35.2)

8 (5.4)

1.1 (0.46–2.82)

  

Constipation

 Yes

76 (18.1)

7 (9.2)

2.4 (0.93–6.16)

  

 No

345 (81.9)

14 (4.1)

1

  

Diarrhea

 Yes

120 (28.5)

6 (5.0)

1.0 (0.38–2.65)

  

 No

301 (71.5)

15 (5.0)

1

  

Abdominal pain

 Yes

65 (15.4)

8 (12.3)

3.7 (1.47–9.33)*

3.9 (1.32–11.23)

0.013

 No

356 (84.6)

13 (3.7)

1

  

Cough

 Yes

187 (44.4)

11 (5.9)

1.4 (0.58–3.37)

  

 No

234 (55.6)

10 (4.3)

1

  

Skin rash

 Yes

8 (1.9)

3 (37.5)

13.2 (2.92–59.4)*

11.1 (1.61–76.2)

0.015

 No

413 (98.1)

18 (4.4)

1

1

 
  1. pos Positive, *p-value < 0.05