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Table 1 Origins, characteristics and pattern of resistance of the 30 pneumococcal isolates tested in this study

From: Analysis of amino acid motif of penicillin-binding proteins 1a, 2b, and 2x in invasive Streptococcus pneumoniae nonsusceptible to penicillin isolated from pediatric patients in Casablanca, Morocco

Strain no. Sources Age (year) Year of isolation Serotype MIC (mg/L) Resistance profile
PG AMX CRO
Penicillin-susceptible
 1 Blood 0.3 2014 1 0.008 0.003 0.008 Wild
 2 CSF 0.3 2013 8 0.016 0.016 0.016 Wild
 3 CSF 1 2012 9V 0.016 0.016 0.008 Wild
 4 Blood 0.1 2011 2 0.016 0.016 0.008 Wild
 5 PF 0.7 2010 6B 0.016 0.016 0.016 Wild
Penicillin-intermediate
 6 Blood 0.1 2013 6B 0.125 0.06 0.004 PG, Ery, TE
 7 CSF 0.4 2008 23F 0.125 0.032 0.064 PG
 8 Blood 5 2008 6A 0.125 0.125 0.25 PG, Ery
 9 Blood 4 2007 19F 0.125 0.25 0.25 PG, SXT, TE
 10 Blood 3 2007 22F 0.25 0.064 0.032 PG
 11 CSF 3 2012 14 0.5 0.25 0.25 PG, SXT
 12 Pus 4 2011 19A 0.5 0.5 0.25 PG, Ery, TE
 13 CSF 0.6 2013 6B 1 0.12 0.25 PG, Ery, TE
 14 CSF 3 2010 6B 1 2 0.5 PG, Ery, SXT, TE
 15 Blood 4 2014 14 1 1 0.5 PG, SXT, TE
Penicillin-resistant
 16 Blood 0.5 2009 14 2 1 1 PG, SXT
 17 CSF 0.5 2010 14 2 2 1 PG, SXT
 18 CSF 0.3 2010 14 2 4 0.25 PG, SXT
 19 PF 3 2011 14 2 1 0.5 PG, Ery, SXT, TE
 20 CSF 1 2009 23F 2 4 0.5 PG, Ery, SXT, Chl, TE
 21 Blood 0.3 2007 14 2 2 0.5 PG, SXT
 22 Blood 3 2013 14 2 1 0.5 PG
 23 Blood 0.6 2011 14 2 2 0.5 PG
 24 Blood 1 2007 14 2 2 0.75 PG, SXT
 25 Pus 0.8 2009 6B 2 2 0.5 PG, Ery, SXT, Chl, TE
 26 Blood 0.5 2013 14 2 0.5 0.5 PG, SXT
 27 Blood 0.4 2010 9V 2 4 0.5 PG, SXT
 28 Blood 1 2009 14 2 2 0.5 PG, SXT
 29 CSF 1.3 2010 14 2 2 0.5 PG, SXT
 30 Blood 3 2011 14 2 1 0.25 PG, SXT
  1. CSF cerebrospinal fluid, PF pleural fluid, MIC minimal inhibitory concentration, PG penicillin G, AMX amoxicillin, CRO ceftriaxone, SXT cotrimoxazole, TE tetracycline, Ery erythromycin, Chl chloramphenicol