Strain no. | Penicillin-binding protein motifs | pbp profile | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
PBP1a | PBP2b | PBP2x | plp1a | plp2b | plp2x | |||||||
STMK (370–373) | SRNVP (428–432) | KTG (557−559) | SVVK (385–388) | SNNT (442–445) | KTGTA (614–618) | STMK (337–340) | HSSN (395–397) | LKSG (546–549) | ||||
Penicillin-susceptible | ||||||||||||
1 | −−−− | −−−− | −−−− | −−−− | −−−− | −−−−− | −−−− | −−−− | −−−− | 5 | 11 | 7 |
2 | −−−− | −−−−− | −−− | −−−− | −−−− | −−−−− | −−−− | −−−− | −−−− | 5 | 1 | 7 |
3 | −−−− | −−−−− | −−− | −−−− | −−−− | −−−−− | −−−− | −−−− | −−−− | 5 | 2 | 7 |
4 | −−−− | −−−−− | −−− | −−−− | −−−− | −−−−− | −−−− | −−−− | −−−− | 5 | 2 | 7 |
5 | −−−− | −−−−− | −−− | −−−− | −−−− | −−−−− | −−−− | −−−− | −−−− | 5 | 2 | 7 |
Penicillin intermediate | ||||||||||||
6 | −−−− | −−−−− | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 5 | 10 | 7 |
7 | −−−− | −−−−− | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 4 | 5 | 9 |
8 | −A−− | −−−−− | −−− | −−−− | −−−A | −−−−− | −−−− | −−−− | −−−− | 6 | 8 | 8 |
9 | −A−− | −−−−T | −−− | −−−− | −−−− | −−−−− | −−−− | L−−− | −−−− | 3 | 2 | 4 |
10 | −−−− | −−−−− | −−− | −−−− | −−−A | −−−−− | −−−− | −−−− | −−−− | 5 | 9 | 3 |
11 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 4 | 6 |
12 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 7 | 1 |
13 | −−−− | −−−−− | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 5 | 3 | 2 |
14 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−G | −A−− | −−−− | V−−− | 2 | 6 | 7 |
15 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 4 | 6 |
Penicillin resistant | ||||||||||||
16 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 4 | 6 |
17 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 4 | 6 |
18 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−G | −A−− | −−−− | V−−− | 1 | 8 | 5 |
19 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 4 | 10 |
20 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 4 | 6 |
21 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 4 | 1 |
22 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 4 | 5 |
23 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 2 | 2 |
24 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 4 | 7 |
25 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 6 | 7 |
26 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 4 | 6 |
27 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 6 | 6 |
28 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 4 | 1 |
29 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 2 | 4 | 6 |
30 | −A−− | −−−−T | −−− | −−−− | −−−A | −−−−− | −A−− | −−−− | V−−− | 1 | 1 | 1 |