TY - JOUR AU - Huang, FengFei AU - Ben Aissa, Manel AU - Lévesque, Georges AU - Carreau, Madeleine PY - 2018 DA - 2018/09/12 TI - FANCC localizes with UNC5A at neurite outgrowth and promotes neuritogenesis JO - BMC Research Notes SP - 662 VL - 11 IS - 1 AB - The Uncoordinated 5A (UNC5A) protein is part of a family of receptors that play roles in axonal pathfinding and cell migration. We previously showed that the Fanconi anemia C protein (FANCC) interacts with UNC5A and delays UNC5A-mediated apoptosis. FANCC is a predominantly cytoplasmic protein that has multiple functions including DNA damage signaling, oxygen radical metabolism, signal transduction, transcriptional regulation and apoptosis. Given the direct interaction between FANCC and UNC5A and that FANCC interferes with UNC5A-mediated apoptosis, we explored the possibility that FANCC might play a role in axonal-like growth processes. SN - 1756-0500 UR - https://doi.org/10.1186/s13104-018-3763-1 DO - 10.1186/s13104-018-3763-1 ID - Huang2018 ER -