TY - JOUR AU - Ramezani, Amir AU - Alipouratigh, Mahin AU - Eng, Lars AU - Turkina, Maria V. AU - Lönn, Johanna AU - Theodorsson, Annette AU - Nayeri, Fariba PY - 2018 DA - 2018/09/12 TI - One-minute through test to distinguish lower respiratory infection by analysis of sputum; exploring the mechanisms JO - BMC Research Notes SP - 664 VL - 11 IS - 1 AB - Cough and fever are the initial symptoms of lower respiratory infection. Severe cases might be fatal. Therefore, particularly in the non-equipped centers, the lack of diagnostic methods to identify the severe cases has resulted in overconsumption of antibiotics. On the basis of the knowledge about non-specific immune response at the site of injury, we developed a colorimetric dip-test that shows abrupt, sensitive and quite specific color change upon contact with sputum in the cases of lower respiratory infection. We further explored the mechanism of the test. SN - 1756-0500 UR - https://doi.org/10.1186/s13104-018-3771-1 DO - 10.1186/s13104-018-3771-1 ID - Ramezani2018 ER -