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Table 1 Association analysis of allele frequency and genotype distribution for polymorphism rs7081455 in POAG cases and controls

From: Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort

SNP (gene) rs7081455 (PLXDC2)
Controls (n = 164)
No. (%)
POAG (n = 188)
No. (%)
Odds ratio 95% confidence interval p valuea
Allelic analysis
 T 145 (44.0) 182 (48.0) 1 Reference
 G* 183 (56.0) 194 (52.0) 1.30 0.86–1.97 0.197
HWE P 0.117 0.388
Genotype and model analysis
 TT 37 (22.5) 47 (25.0) 1 Reference
 TG 71 (43.3) 88 (46.8) 1.02 0.60–1.74 0.920
 GG 56 (34.1) 53 (28.2) 1.34 0.75–2.37 0.312
Additive 0.482
Dominant 1.14 0.69–1.87 0.590
Recessive 1.32 0.84–2.07 0.228
  1. HWE P Hardy–Weinberg equilibrium p value
  2. aPearson Chi2 test
  3. * Risk variant