Table 1 Association analysis of allele frequency and genotype distribution for polymorphism rs7081455 in POAG cases and controls
SNP (gene) | rs7081455 (PLXDC2) | ||||
|---|---|---|---|---|---|
Controls (n = 164) No. (%) | POAG (n = 188) No. (%) | Odds ratio | 95% confidence interval | p valuea | |
Allelic analysis | |||||
T | 145 (44.0) | 182 (48.0) | 1 | Reference | – |
G* | 183 (56.0) | 194 (52.0) | 1.30 | 0.86–1.97 | 0.197 |
HWE P | 0.117 | 0.388 | – | – | – |
Genotype and model analysis | |||||
TT | 37 (22.5) | 47 (25.0) | 1 | Reference | – |
TG | 71 (43.3) | 88 (46.8) | 1.02 | 0.60–1.74 | 0.920 |
GG | 56 (34.1) | 53 (28.2) | 1.34 | 0.75–2.37 | 0.312 |
Additive | – | – | – | – | 0.482 |
Dominant | – | – | 1.14 | 0.69–1.87 | 0.590 |
Recessive | – | – | 1.32 | 0.84–2.07 | 0.228 |