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Table 2 Genotype effect on demographic and clinical characteristics within PAOG group

From: Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort

Characteristics Genotypes p valuea
T/T (n = 47)
No. (%)
T/G (n = 88)
No. (%)
G/G (n = 53)
No. (%)
Demographic
 Age in years, mean (SD) 59.0 (11.3) 61.2 (11.0) 62.2 (9.4) 0.305*
 Male 27 (57.4) 49 (55.6) 28 (52.8) 0.894
 Female 20 (42.5) 39 (44.3) 25 (47.1)
Medical history
 Family history of glaucoma 5 (10.6) 7 (7.9) 6 (11.3) 0.773
 Smoking 8 (17.0) 7 (7.9) 5 (9.4) 0.251
 Diabetes mellitus 18 (38.3) 37 (42.0) 20 (37.7) 0.851
 Hypertension 15 (31.9) 34 (38.6) 22 (41.5) 0.598
 Coronary artery disease 1 (2.1) 3 (3.4) 2 (3.7) 0.885
 Hypercholesterolemia 1 (2.1) 7 (7.9) 5 (9.4) 0.310
Glaucoma indices
 Intraocular pressure, mmHg, mean (SD) 22.3 (8.1) 23.7 (8.8) 23.2 (10.3) 0.536**
 Cup/disc ratio 0.77 (0.2) 0.81 (0.6) 0.75 (0.2) 0.736**
 Number of anti-glaucoma medications 1.6 (0.9) 1.9 (1.1) 1.8 (1.2) 0.214**
  1. aPearson Chi2 test
  2. * One-way ANOVA
  3. ** Kruskal–Wallis test