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Table 1 Summary of DNA glycosylase activity rate constants for hOGG1 variants

From: Thermostability and excision activity of polymorphic forms of hOGG1

hOGG1 variant A0 (nM) k1 (min−1) k2 (nM min−1)
Wild-type 14.2 ± 0.3 1.4 ± 0.1 0.09 ± 0.01
R46Q 10.5 ± 0.6 2.0 ± 0.6 0.14 ± 0.03
A85S 14.3 ± 0.3 1.6 ± 0.1 0.08 ± 0.01
R154H 8.4 ± 0.6 0.23 ± 0.03 0.14 ± 0.01
S232T 10.5 ± 0.5 0.8 ± 0.1 0.15 ± 0.02