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Table 1 Inflammatory biomarkers of patients at baseline and after 3 month

From: Inflammatory markers response to citrulline supplementation in patients with non-alcoholic fatty liver disease: a randomized, double blind, placebo-controlled, clinical trial

Characteristics Baseline Mean ± SD After 3 month Mean ± SD P* Change Mean ± SD P
hs-CRP (ng/ml)
Cit 5696 ± 2862 3901 ± 2760 < 0.01 − 1794 ± 2025 0.02
Placebo 6323 ± 4812 6143 ± 4851 0.713 − 180.6 ± 1866  
TNF-α (pg/ml)
Cit 15.1 ± 4.74 14.6 ± 2.01 0.66 − 0.55 ± 0.07 0.57
Placebo 18.5 ± 2.04 17.4 ± 1.57 0.05 − 1.29 ± 2.37  
NF-κb (ng/mg protein)
Cit 2.46 ± 0.72 2.11 ± 0.42 0.02 − 0.30 ± 0.63 < 0.001
Placebo 1.99 ± 1.34 2.64 ± 0.72 0.09 0.64 ± 1.29  
  1. TNF-α tumor necrosis factor α, hs-CRP C_reactive protein, NF-κB nuclear factor kappa B cells
  2. * P values indicate comparison within groups
  3. P values indicate comparison between the changes of each variable between two groups