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Table 3 Genomic, mRNA and transcriptomic GC contents in the investigated human conditions and other species

From: On the length, weight and GC content of the human genome

Species Genomic GC% mRNA GC% Transcriptomic GC% ∆GC%(mRNA−Genomic) ∆GC%(Transcriptomic−mRNA)
H. sapiens DS-AMKL 40.89 48.80 48.21 7.91 − 0.59
H. sapiens MK 49.27 7.91 0.47
H. sapiens Hippocampus 48.83 48.85 7.94 0.03
H. sapiens Brain 48.92 7.94 0.09
D. rerio Brain 36.63 45.70 45.40 9.08 − 0.30
C. elegans 35.44 42.21 43.22 6.77 1.00
S. cerevisiae 38.30 39.63 40.21 1.34 0.58
E. coli 50.79 51.99 52.13 1.20 0.15
  1. Genomic GC%: percentage of G (guanine), C (cytosine) and S (G or C, present only in H. sapiens and D. rerio assemblies); for H. sapiens the mean GC content between male and female genomes was used; mRNA GC%: percentage of G and C in the analysed messenger RNA set having an expression value together with mRNA sequences available (see “Methods” section for details); transcriptomic GC%: percentage of G and C in the sum of each mRNA GC count multiplied by its mean expression value for each biological condition; ∆GC%(mRNA−Genomic): difference between mRNA and genomic GC%; ∆GC%(Transcriptomic−mRNA): difference between transcriptomic and mRNA GC%