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Fig. 3 | BMC Research Notes

Fig. 3

From: INC280 inhibits Wnt/β-catenin and EMT signaling pathways and its induce apoptosis in diffuse gastric cancer positive for c-MET amplification

Fig. 3

Effect of c-MET downregulation on RUNX3, SNAIL and the Wnt/β-catenin signaling pathway. mRNA expression of c-MET-RUNX3-regulated genes in MKN28 (a) and MKN45 (b) cells. c Protein levels of c-MET-RUNX3-regulated genes in MKN28 and MKN45 cells. ***p < 0.001. d A presentative confocal microscopy showing decreased of membrane bound β-catenin in INC280 treated MKN45 cells

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