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Table 1 Factors associated with increased risk for developing T2DM based on risk scores

From: Type 2 diabetes mellitus prevalence and risk scores in treated PLWHIV: a cross-sectional preliminary study

Variables

N = 234

Low risk (< 7 scores), n = 135 (58%)

Increased risk (≥ 7 scores), n = 99 (42%)

p value

Age, median years (IQR)

44 (36, 52)

42 (34, 50)

48 (39, 56)

< 0.001

Age category (years)

 18–35

57 (24.4)

45 (33.3)

12 (12.1)

< 0.001

 36–45

73 (32.3)

49 (36.3)

24 (24.2)

 

 46–55

66 (28.2)

29 (21.5)

37 (37.4)

 

 56–65

33 (14.1)

9 (6.7)

24 (24.2)

 

 66–90

5 (2.1)

3 (2.2)

2 (2.0)

 

Gender, n (%)

 Female

155 (66.2)

76 (56.3)

79 (79.8)

< 0.001

 Male

79 (33.8)

59 (43.7)

20 (20.2)

 

BMI, median (IQR) kg/m2

22.4 (19.7, 27.1)

21.1 (18.6, 22.6)

27.3 (23.6, 31.0)

< 0.001

Waist circumference (cm)

80 (72, 90)

76.0 (70.0, 80.0)

92.0 (83.0, 99.5)

< 0.001

Duration on ART, median months (IQR), n = 233

96 (48, 132)

84 (60, 126)

96 (48, 138)

0.221

ART regimen, n = 206

 TDF/3TC/EFV

148 (71.8)

81 (69.2)

67 (75.3)

0.811

 TDF/3TC/NVP

19 (9.2)

10 (8.5)

9 (10.1)

 

 TDF/3TC/LPV/r

15 (7.3)

9 (7.7)

6 (6.7)

 

 ABC/3TC/NVP

1 (0.5)

1 (0.9)

0 (0.0)

 

 ABC/3TC/EFV

5 (2.4)

3 (2.6)

2 (2.2)

 

 AZT/3TC/LPV/r

7 (3.4)

5 (4.3)

2 (2.2)

 

 AZT/3TC/NVP

11 (5.3)

8 (6.8)

3 (3.4)

 

CD4+ absolute count median (IQR) cells/µl, n = 148

473 (360, 644)

435 (306, 599)

544 (398, 674)

0.345

HIV RNA viral load (copies/ml), n = 192

33 (20, 308)

31 (20, 273)

20 (20, 186)

0.724

Hypertension

 No

197 (84.2)

126 (93.3)

71 (71.7)

< 0.001

 Yes

37 (15.8)

9 (6.7)

28 (28.3)

 

Minutes of weekly vigorous activity

0 (0, 90)

0 (0, 120)

0 (0, 105)

0.234

Minutes of weekly moderate activity

60 (9, 123)

45 (0, 120)

60 (8, 120)

0.875

Minutes of weekly walking activity

60 (30, 120)

60 (30, 120)

40 (18, 70)

0.293

Days of weekly vegetable intake

7 (7, 7)

7 (7, 7)

7 (4, 7)

0.028

Days of weekly fruit intake

1 (0, 3)

1 (0, 3)

1 (0, 3)

0.770

Minutes spend sited every weekend

300 (120, 480)

300 (120, 375)

300 (180, 420)

0.086

Minutes spend sited every weekday

180 (120, 360)

180 (90, 303)

180 (120, 360)

0.501

Fasting blood sugar

5.2 (4.7, 5.8)

5.1 (4.7, 5.5)

5.2 (4.8, 5.9)

0.110

  1. n number of participants, % percentage, BMI body mass index, T2DM type 2 diabetes mellitus, IQR interquartile range, TDF tenofovir disoproxil fumarate, 3TC lamivudine, EFV efavirenz, NVP nevirapine; LPV/r lopinavir/ritonavir, ABC abacavir, AZT azidothymidine, also called zidovudine
  2. p values less than 0.05 are shown in italic