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Table 3 Factors associated with cognitive impairment among MDD patients at AMSH, Addis Ababa, Ethiopia (n = 395)

From: Magnitude and correlates of cognitive impairment among major depressive disorder patients in Addis Ababa: institution based cross-sectional study

Variables Categories Cognitive impairment COR, CI (95%) AOR, CI (95%)
No Yes
Sex Male 104 92 1 1
Female 76 123 1.83 (1.23, 2.73) 1.65 (0.93, 2.93)
Age 18–25 67 35 1 1
26–40 74 76 1.96 (1.17, 3.30) 1.43 (0.73, 2.79)
41–59 39 104 5.11 (3.87, 12.57) 3:00 (1.49, 6.03)***
Presence of occupation Yes 142 98 1 1
No 38 117 4.46 (2.85, 6.98) 3.13 (1.76, 5.59)***
Education Can’t read and write 14 80 7.56 (3.68, 15.56) 5.92 (2.45, 14.28)***
1–8 grade 51 63 1.64 (0.92, 2.92) 1.49 (0.72, 3.13)
9–12 grade 70 38 0.72 (0.39, 1.30) 0.68 (0.34, 1.48)
Diploma and above 45 34 1 1
Co-morbidity Yes 71 127 2.22 (1.48, 3.32) 2.16 (1.26, 3.71)*
No 109 88 1 1
Treatment duration (years) < 6 128 114 1 1
< 6 52 101 2.18 (1.43, 3.32) 1.53 (0.69, 3.39)
Relapse history Yes 56 116 2.59 (1.72, 3.93) 2.97 (1.54, 5.73)**
No 124 99 1 1
Duration of illness (years) < 5 28 15 1 1
5–10 45 10 0.42 (0.16, 1.05) 0.48 (0.15, 1.54)
< 10 107 190 3.32 (1.69, 6.48) 3.16 (1.31, 7.64)**
Previous hospitalization Yes 48 104 2.58 (1.68, 3.94) 1.28 (0.66, 2.49)
No 132 111 1 1
  1. * p-value significant at p < 0.05, ** p-value is significant at p < 0.01, *** p-value is significant at p < 0.001 and p-value from Hosmer and Lemeshow test was 0.745
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