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Table 3 Factors associated with cognitive impairment among MDD patients at AMSH, Addis Ababa, Ethiopia (n = 395)

From: Magnitude and correlates of cognitive impairment among major depressive disorder patients in Addis Ababa: institution based cross-sectional study

Variables

Categories

Cognitive impairment

COR, CI (95%)

AOR, CI (95%)

No

Yes

Sex

Male

104

92

1

1

Female

76

123

1.83 (1.23, 2.73)

1.65 (0.93, 2.93)

Age

18–25

67

35

1

1

26–40

74

76

1.96 (1.17, 3.30)

1.43 (0.73, 2.79)

41–59

39

104

5.11 (3.87, 12.57)

3:00 (1.49, 6.03)***

Presence of occupation

Yes

142

98

1

1

No

38

117

4.46 (2.85, 6.98)

3.13 (1.76, 5.59)***

Education

Can’t read and write

14

80

7.56 (3.68, 15.56)

5.92 (2.45, 14.28)***

1–8 grade

51

63

1.64 (0.92, 2.92)

1.49 (0.72, 3.13)

9–12 grade

70

38

0.72 (0.39, 1.30)

0.68 (0.34, 1.48)

Diploma and above

45

34

1

1

Co-morbidity

Yes

71

127

2.22 (1.48, 3.32)

2.16 (1.26, 3.71)*

No

109

88

1

1

Treatment duration (years)

< 6

128

114

1

1

< 6

52

101

2.18 (1.43, 3.32)

1.53 (0.69, 3.39)

Relapse history

Yes

56

116

2.59 (1.72, 3.93)

2.97 (1.54, 5.73)**

No

124

99

1

1

Duration of illness (years)

< 5

28

15

1

1

5–10

45

10

0.42 (0.16, 1.05)

0.48 (0.15, 1.54)

< 10

107

190

3.32 (1.69, 6.48)

3.16 (1.31, 7.64)**

Previous hospitalization

Yes

48

104

2.58 (1.68, 3.94)

1.28 (0.66, 2.49)

No

132

111

1

1

  1. * p-value significant at p < 0.05, ** p-value is significant at p < 0.01, *** p-value is significant at p < 0.001 and p-value from Hosmer and Lemeshow test was 0.745