TY - JOUR AU - Tarimo, Brian B. AU - Hritzo, Bernadette A. AU - Law, Henry Chun Hin AU - Tao, Dingyin AU - Pastrana-Mena, Rebecca AU - Kanzok, Stefan M. AU - Buza, Joram J. AU - Dinglasan, Rhoel R. PY - 2019 DA - 2019/03/29 TI - Ribosomal/nucleolar stress induction regulates tert-Butyl hydroperoxide (tBHP) mediated oxidative stress in Anopheles gambiae midguts JO - BMC Research Notes SP - 182 VL - 12 IS - 1 AB - A fundamental understanding of redox homeostasis in Anopheles gambiae midgut cells under different oxidative conditions is missing. Such knowledge can aid in the development of new malaria transmission-blocking strategies aimed at disrupting natural homeostatic processes in the mosquito during Plasmodium parasite uptake (i.e. blood feeding). The aim of this study was to understand how the An. gambiae midgut regulates oxidative stress to reactive oxygen species (ROS), especially to a potent ROS-inducer such as tert-Butyl hydroperoxide (tBHP). SN - 1756-0500 UR - https://doi.org/10.1186/s13104-019-4196-1 DO - 10.1186/s13104-019-4196-1 ID - Tarimo2019 ER -