Fig. 1

Prevention in apoE KO mice. Values are expressed as mean ± SEM (a, b) or mean with scatter plots (c–e) (n = 16). (A) Body weight change. b Food intake. c Lesion area in en face analysis. **P < 0.01 as compared with control. d Cholesterol content in aorta. **P < 0.01 as compared with control. e Lesion area of aortic root (n = 5–7). *P < 0.05 as compared with control. f Aorta with Sudan IV staining. g Histological features using serial cross sections subjected to HE, EvG and anti Mac-3 antigen. In the EvG staining, elastic fibers and nuclei appear in dark purple, collagen fibers in red, smooth muscle and cytosol between internal and external laminae in yellow