Fig. 2

Dynamic response of cfDNA in patient P17 in two consecutive cycles of chemotherapy. cfDNA was isolated from plasma samples collected pre, post and 24Â h after infusion of docetaxel at cycles 1 and 2, 21Â days apart. a PSA plotted over time. Doc markings indicate treatment start dates. b LINE1 qPCR to quantify cfDNA dynamics. c Mutation frequencies of T878A and H875Y AR