TY - JOUR AU - Palanisamy, Karthikka AU - Karunakaran, Coral AU - Raman, Rajiv AU - Chidambaram, Subbulakshmi PY - 2019 DA - 2019/05/30 TI - Optimization of an in vitro bilayer model for studying the functional interplay between human primary retinal pigment epithelial and choroidal endothelial cells isolated from donor eyes JO - BMC Research Notes SP - 307 VL - 12 IS - 1 AB - The microenvironment of outer retina is largely regulated by retinal pigment epithelium (RPE) and choroid. Damage to either of these layers lead to the development of age related macular degeneration (AMD). A simplified cell culture model that mimics the RPE/Bruch’s membrane (BM) and choroidal layers of the eye is a prerequisite for elucidating the molecular mechanism of disease progression. SN - 1756-0500 UR - https://doi.org/10.1186/s13104-019-4333-x DO - 10.1186/s13104-019-4333-x ID - Palanisamy2019 ER -