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TableĀ 1 Alternative splicing of NCoR-1 and NCoR-2 corepressors

From: Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals

Species

NCoR-1

NCoR-2

28b+

28bāˆ’

37b+

37bāˆ’

45a+

45aāˆ’

45āˆ’

28b+

28bāˆ’

40b+

40bāˆ’

47b+

47bāˆ’

47āˆ’

Alligator

100

ND

100

ND

100

ND

ND

100

ND

29.0 (4.4)

71.0 (4.4)

22.4 (5.3)

40.0 (6.0)

37.6 (5.3)

Bat

100

ND

73.1 (8.7)

26.9 (8.7)

100

ND

ND

100

ND

52.5 (9.0)

47.5 (9.0)

*

*

*

Cat

100

ND

59.8 (1.7)

40.2 (1.7)

49.0 (2.3)

ND

51.0 (2.3)

100

ND

25.1 (1.2)

74.9 (1.2)

100

ND

ND

Chicken

100

ND

100

ND

100

ND

ND

100

ND

ND

100

24.6 (3.8)

41.8 (3.9)

33.6 (3.6)

Dog

100

ND

64.4 (3.9)

35.6 (3.9)

59.5 (2.2)

ND

40.5 (2.2)

100

ND

21.7 (2.6)

78.3 (2.6)

28.0 (4.5)

72.0 (4.5)

ND

Elephant

100

ND

89.4 (3.3)

10.6 (3.3)

100

ND

ND

100

ND

30.4 (2.9)

69.6 (2.9)

24.3 (3.1)

46.0 (5.3)

29.7 (5.5)

Horse

100

ND

69.3 (6.8)

30.7 (6.8)

100

ND

ND

100

ND

26.8 (5.4)

73.2 (5.4)

ND

46.4 (6.6)

53.6 (6.6)

Human

100

ND

70.2 (5.5)

29.8 (5.5)

100

ND

ND

86.0 (2.5)

14.0 (2.5)

17.5 (3.9)

82.5 (3.9)

20.4 (1.8)

53.6 (1.5)

26.0 (1.9)

Mouse

76.2 (0.2)

23.8 (0.2)

54.2 (2.4)

45.8 (2.4)

88.8 (0.9)

11.2 (0.9)

ND

86.9 (2.7)

13.1 (2.7)

32.9 (2.3)

67.1 (2.3)

17.2 (1.8)

61.2 (4.2)

21.6 (2.8)

Pig

100

ND

55.0 (1.5)

45.0 (1.5)

100

ND

ND

100

ND

27.9 (0.6)

72.1 (0.6)

ND

64.5 (1.7)

35.5 (1.7)

Rabbit

100

ND

63.8 (1.3)

36.2 (1.3)

100

ND

ND

100

ND

15.2 (1.1)

84.8 (1.1)

ND

54.4 (3.4)

45.6 (3.4)

Rat

73.2 (1.7)

26.8 (1.7)

58.0 (3.6)

42.0 (3.6)

100

ND

ND

100

ND

32.8 (2.0)

67.2 (2.0)

17.3 (2.1)

60.3 (1.6)

22.3 (3.1)

Rhesus

100

ND

63.8 (5.4)

36.2 (5.4)

100

ND

ND

69.7 (2.6)

30.2 (2.6)

19.5 (3.0)

80.5 (3.0)

19.5 (2.1)

58.6 (6.1)

22.0 (6.4)

  1. Alternative mRNA splicing was determined as described in "Methods" and Additional file 1 from RNA isolated from peripheral blood from each species listed (Alligator, Alligator mississippiensis; Bat, Eidolon helvum; Cat, Felis silvestris catus; Chicken, Gallus gallus domesticus; Dog, Canis lupus familiaris; Elephant, Loxodonta africana; Horse, Equus ferus caballus, Human, Homo sapien; Mouse, Mus musculus; Pig, Sus scrofa domesticus; Rabbit, Oryctolagus cuniculus; Rat, Rattus norvegicus; Rhesus, Macaca mulatta). Results from an individual of each species are presented. The relative abundance of each alternative-splice variant from each splice site analyzed is presented as a percent of the total splice variants expressed from that site (sumā€‰=ā€‰100%)
  2. NDā€‰=ā€‰not detected (limits of detection were estimated asā€‰<ā€‰2% of total expression at each splice site, the limits of accurate quantitation asā€‰>ā€‰5%). The structures of the alternative-spliced transcripts are detailed in [23] except for the NCoR-1 exon 45āˆ’ splice variant, which was newly recognized from the current analysis and was confirmed by sequence analysis of the PCR products. The mean and (standard error) of 3 or more analyzes are shown for each value
  3. * Data not available. See ā€œLimitationsā€ and Additional file 1 for an expanded discussion of the sensitivity and accuracy of this RT-PCR methodology