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Table 1 Effects of treatments on rat bodyweight gains, organ weights and liver enzymatic activities

From: Co-administration of a Rhododendron tomentosum extract does not affect mercury tissue concentrations and excretion rate in methylmercury-treated adult male rats

 

Control

Labrador Tea

Antibiotics

MeHg

MeHg + Labrador Tea

MeHg + antibiotics

Body weight gain (g)

78.0 ± 15.6

84.4 ± 8.0

82.9 ± 17.1

75.3 ± 22.1

75.7 ± 20.8

76.8 ± 21.2

Kidney weight, absolute (g)

2.20 ± 0.25

2.25 ± 0.24

2.24 ± 0.25

2.35 ± 0.22

2.41 ± 0.13

2.25 ± 0.26

Kidney weight, relative (%)

0.609 ± 0.029

0.606 ± 0.028

0.613 ± 0.029

0.657 ± 0.042

0.659 ± 0.055

0.615 ± 0.050

Liver weight, absolute (g)

12.64 ± 2.42

12.98 ± 0.88

10.60 ± 1.37

11.78 ± 1.06

12.44 ± 1.88

10.32 ± 1.34*

Liver weight, relative (%)

3.50 ± 0.17

3.50 ± 0.16

2.89 ± 0.17*

3.29 ± 0.19

3.37 ± 0.23

2.81 ± 0.16*

Liver enzymatic activities

 BROD (pmol/min/mg prot)

42.7 ± 18.7

88.6 ± 26.3

105.5 ± 49.1*

62.2 ± 23.4

84.0 ± 41.4

103.2 ± 36.3*

 EROD (pmol/min/mg prot)

54.1 ± 24.4

88.4 ± 22.5

93.4 ± 37.6*

28.0 ± 18.6

63.8 ± 28.4

69.4 ± 21.7

 PROD (pmol/min/mg prot)

17.3 ± 7.0

30.0 ± 8.8

33.5 ± 13.1*

16.6 ± 6.9

19.5 ± 10.0

22.1 ± 8.8

 GGT (mU/g prot)

93.7 ± 51.0

113.2 ± 34.0

146.1 ± 30.1

102.9 ± 76.9

100.1 ± 32.5

79.8 ± 33.2

  1. Mean ± SD of seven animals per treatment group
  2. EROD: ethoxyresorufin-O-deethylase; BROD: benzyloxyresorufin-O-dealkylase; PROD: pentoxyresorufin-O-dealkylase; GGT: gamma glutamyl transferase
  3. * Significantly different from control group values (P < 0.05) as assessed by one-way ANOVA followed by Dunnett post hoc test