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Table 1 Effects of treatments on rat bodyweight gains, organ weights and liver enzymatic activities

From: Co-administration of a Rhododendron tomentosum extract does not affect mercury tissue concentrations and excretion rate in methylmercury-treated adult male rats

  Control Labrador Tea Antibiotics MeHg MeHg + Labrador Tea MeHg + antibiotics
Body weight gain (g) 78.0 ± 15.6 84.4 ± 8.0 82.9 ± 17.1 75.3 ± 22.1 75.7 ± 20.8 76.8 ± 21.2
Kidney weight, absolute (g) 2.20 ± 0.25 2.25 ± 0.24 2.24 ± 0.25 2.35 ± 0.22 2.41 ± 0.13 2.25 ± 0.26
Kidney weight, relative (%) 0.609 ± 0.029 0.606 ± 0.028 0.613 ± 0.029 0.657 ± 0.042 0.659 ± 0.055 0.615 ± 0.050
Liver weight, absolute (g) 12.64 ± 2.42 12.98 ± 0.88 10.60 ± 1.37 11.78 ± 1.06 12.44 ± 1.88 10.32 ± 1.34*
Liver weight, relative (%) 3.50 ± 0.17 3.50 ± 0.16 2.89 ± 0.17* 3.29 ± 0.19 3.37 ± 0.23 2.81 ± 0.16*
Liver enzymatic activities
 BROD (pmol/min/mg prot) 42.7 ± 18.7 88.6 ± 26.3 105.5 ± 49.1* 62.2 ± 23.4 84.0 ± 41.4 103.2 ± 36.3*
 EROD (pmol/min/mg prot) 54.1 ± 24.4 88.4 ± 22.5 93.4 ± 37.6* 28.0 ± 18.6 63.8 ± 28.4 69.4 ± 21.7
 PROD (pmol/min/mg prot) 17.3 ± 7.0 30.0 ± 8.8 33.5 ± 13.1* 16.6 ± 6.9 19.5 ± 10.0 22.1 ± 8.8
 GGT (mU/g prot) 93.7 ± 51.0 113.2 ± 34.0 146.1 ± 30.1 102.9 ± 76.9 100.1 ± 32.5 79.8 ± 33.2
  1. Mean ± SD of seven animals per treatment group
  2. EROD: ethoxyresorufin-O-deethylase; BROD: benzyloxyresorufin-O-dealkylase; PROD: pentoxyresorufin-O-dealkylase; GGT: gamma glutamyl transferase
  3. * Significantly different from control group values (P < 0.05) as assessed by one-way ANOVA followed by Dunnett post hoc test