| |
Control
|
Labrador Tea
|
Antibiotics
|
MeHg
|
MeHg + Labrador Tea
|
MeHg + antibiotics
|
|---|
|
RBC (× 106 cells/µL)
|
7.54 ± 0.46
|
7.59 ± 0.15
|
7.93 ± 0.32
|
7.83 ± 0.32
|
7.86 ± 0.29
|
7.75 ± 0.37
|
|
HGB (g/dL)
|
14.36 ± 0.49
|
14.11 ± 0.34
|
14.37 ± 0.43
|
14.39 ± 0.29
|
14.37 ± 0.61
|
14.33 ± 0.54
|
|
HCT (%)
|
42.31 ± 1.95
|
42.01 ± 1.50
|
43.50 ± 1.08
|
43.84 ± 1.35
|
43.67 ± 1.92
|
43.57 ± 1.82
|
|
MCV (fL)
|
56.20 ± 1.10
|
55.36 ± 1.18
|
54.95 ± 1.42
|
56.03 ± 1.77
|
55.53 ± 1.69
|
56.24 ± 2.00
|
|
MCH (pg)
|
19.07 ± 0.70
|
18.59 ± 0.31
|
18.18 ± 0.43
|
18.4 ± 0.59
|
18.28 ± 0.48
|
18.46 ± 0.59
|
|
MCHC (g/dL)
|
33.94 ± 0.72
|
33.59 ± 0.54
|
33.03 ± 0.64*
|
32.83 ± 0.63*
|
32.88 ± 0.58*
|
32.86 ± 0.32*
|
|
PLT (× 103 cells/µL)
|
867 ± 138
|
1010 ± 68*
|
921 ± 84
|
977 ± 45
|
969 ± 62
|
875 ± 159
|
|
MPV (fL)
|
6.03 ± 1.29
|
6.04 ± 1.11
|
6.08 ± 1.34
|
6.20 ± 1.08
|
6.40 ± 1.38
|
6.20 ± 1.37
|
|
WBC (× 103 cells/µL)
|
4.25 ± 1.57
|
4.62 ± 0.39
|
3.86 ± 1.50
|
5.79 ± 1.72
|
5.13 ± 1.4
|
4.24 ± 1.10
|
|
LYM (× 103 cells/µL)
|
3.21 ± 1.63
|
3.79 ± 0.37
|
3.26 ± 1.47
|
4.35 ± 1.53
|
3.92 ± 1.25
|
3.32 ± 0.75
|
|
NEUT (× 103 cells/µL)
|
0.57 ± 0.46
|
0.41 ± 0.25
|
0.30 ± 0.19
|
0.78 ± 0.90
|
0.5 ± 0.36
|
0.23 ± 0.16
|
|
MONO (× 103 cells/µL)
|
0.23 ± 0.22
|
0.22 ± 0.31
|
0.12 ± 0.12
|
0.32 ± 0.37
|
0.36 ± 0.39
|
0.29 ± 0.29
|
|
EOS (× 103 cells/µL)
|
0.041 ± 0.018
|
0.040 ± 0.008
|
0.040 ± 0.030
|
0.049 ± 0.020
|
0.073 ± 0.077
|
0.053 ± 0.027
|
|
LUC (× 103 cells/µL)
|
0.17 ± 0.14
|
0.14 ± 0.17
|
0.12 ± 0.12
|
0.25 ± 0.32
|
0.23 ± 0.25
|
0.30 ± 0.34
|
|
BASO (× 103 cells/µL)
|
0.03 ± 0.01
|
0.02 ± 0.00
|
0.03 ± 0.01
|
0.04 ± 0.02
|
0.03 ± 0.01
|
0.03 ± 0.02
|
|
LYM (%)
|
73.26 ± 13.50
|
82.01 ± 5.09
|
82.28 ± 7.63
|
75.09 ± 12.07
|
76.03 ± 5.22
|
79.13 ± 7.07
|
|
NEUT (%)
|
14.56 ± 12.89
|
9.06 ± 5.73
|
8.33 ± 5.30
|
14.09 ± 14.28
|
10.42 ± 7.35
|
6.16 ± 4.49
|
|
MONO (%)
|
6.11 ± 6.35
|
4.64 ± 6.40
|
3.65 ± 4.75
|
5.24 ± 5.68
|
7.05 ± 7.82
|
6.31 ± 5.33
|
|
EOS (%)
|
1.04 ± 0.46
|
0.90 ± 0.21
|
1.08 ± 0.73
|
0.91 ± 0.51
|
1.58 ± 1.83
|
1.34 ± 0.57
|
|
LUC (%)
|
4.36 ± 3.93
|
2.96 ± 3.35
|
3.73 ± 4.81
|
4.07 ± 5.04
|
4.33 ± 4.4
|
6.21 ± 6.14
|
|
BASO (%)
|
0.66 ± 0.32
|
0.43 ± 0.10
|
0.93 ± 0.79
|
0.61 ± 0.21
|
0.63 ± 0.18
|
0.89 ± 0.50
|
|
IgG (mg/mL)
|
2.57 ± 0.93
|
3.42 ± 0.93
|
2.77 ± 0.97
|
3.48 ± 1.71
|
5.48 ± 2.21#
|
2.89 ± 1.62
|
|
IgM (µg/mL)
|
108.2 ± 38.9
|
94.8 ± 21.9
|
84.1 ± 18.7
|
218.4 ± 303.5
|
107 ± 18.3
|
85.9 ± 29.8
|
|
IgA (µg/mL)
|
22.7 ± 3.4
|
24.7 ± 2.6
|
24.9 ± 12.0
|
18.7 ± 2.7
|
38.2 ± 11.7
|
22.4 ± 3.2
|
|
IgE (ng/mL)
|
9.2 ± 9.1
|
14.5 ± 26.1
|
6.3 ± 6.1
|
240.3 ± 263.6*
|
410.1 ± 266.7*
|
115.9 ± 199.3*
|
- Mean ± SD of 6–7 animals per treatment group
- RBC: red blood cells; HGB: hemoglobin; HCT: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; PLT: platelet; MPV: mean platelet volume; WBC: white blood cells; LYM: lymphocytes; NEUT: neutrophils; MONO, monocytes; EOS: eosinophils; LUC: large unstained cells; BASO: basophils
- * Significantly different from control group values (P < 0.05) as assessed by one-way ANOVA followed by Dunnett post hoc test
- #Significantly different from control group values (P < 0.05) as assessed by Kruskal–Wallis ANOVA followed by Dunnett post hoc test on ranks
