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Table 2 Effects of treatments on rat hematological parameters

From: Co-administration of a Rhododendron tomentosum extract does not affect mercury tissue concentrations and excretion rate in methylmercury-treated adult male rats

  Control Labrador Tea Antibiotics MeHg MeHg + Labrador Tea MeHg + antibiotics
RBC (× 106 cells/µL) 7.54 ± 0.46 7.59 ± 0.15 7.93 ± 0.32 7.83 ± 0.32 7.86 ± 0.29 7.75 ± 0.37
HGB (g/dL) 14.36 ± 0.49 14.11 ± 0.34 14.37 ± 0.43 14.39 ± 0.29 14.37 ± 0.61 14.33 ± 0.54
HCT (%) 42.31 ± 1.95 42.01 ± 1.50 43.50 ± 1.08 43.84 ± 1.35 43.67 ± 1.92 43.57 ± 1.82
MCV (fL) 56.20 ± 1.10 55.36 ± 1.18 54.95 ± 1.42 56.03 ± 1.77 55.53 ± 1.69 56.24 ± 2.00
MCH (pg) 19.07 ± 0.70 18.59 ± 0.31 18.18 ± 0.43 18.4 ± 0.59 18.28 ± 0.48 18.46 ± 0.59
MCHC (g/dL) 33.94 ± 0.72 33.59 ± 0.54 33.03 ± 0.64* 32.83 ± 0.63* 32.88 ± 0.58* 32.86 ± 0.32*
PLT (× 103 cells/µL) 867 ± 138 1010 ± 68* 921 ± 84 977 ± 45 969 ± 62 875 ± 159
MPV (fL) 6.03 ± 1.29 6.04 ± 1.11 6.08 ± 1.34 6.20 ± 1.08 6.40 ± 1.38 6.20 ± 1.37
WBC (× 103 cells/µL) 4.25 ± 1.57 4.62 ± 0.39 3.86 ± 1.50 5.79 ± 1.72 5.13 ± 1.4 4.24 ± 1.10
LYM (× 103 cells/µL) 3.21 ± 1.63 3.79 ± 0.37 3.26 ± 1.47 4.35 ± 1.53 3.92 ± 1.25 3.32 ± 0.75
NEUT (× 103 cells/µL) 0.57 ± 0.46 0.41 ± 0.25 0.30 ± 0.19 0.78 ± 0.90 0.5 ± 0.36 0.23 ± 0.16
MONO (× 103 cells/µL) 0.23 ± 0.22 0.22 ± 0.31 0.12 ± 0.12 0.32 ± 0.37 0.36 ± 0.39 0.29 ± 0.29
EOS (× 103 cells/µL) 0.041 ± 0.018 0.040 ± 0.008 0.040 ± 0.030 0.049 ± 0.020 0.073 ± 0.077 0.053 ± 0.027
LUC (× 103 cells/µL) 0.17 ± 0.14 0.14 ± 0.17 0.12 ± 0.12 0.25 ± 0.32 0.23 ± 0.25 0.30 ± 0.34
BASO (× 103 cells/µL) 0.03 ± 0.01 0.02 ± 0.00 0.03 ± 0.01 0.04 ± 0.02 0.03 ± 0.01 0.03 ± 0.02
LYM (%) 73.26 ± 13.50 82.01 ± 5.09 82.28 ± 7.63 75.09 ± 12.07 76.03 ± 5.22 79.13 ± 7.07
NEUT (%) 14.56 ± 12.89 9.06 ± 5.73 8.33 ± 5.30 14.09 ± 14.28 10.42 ± 7.35 6.16 ± 4.49
MONO (%) 6.11 ± 6.35 4.64 ± 6.40 3.65 ± 4.75 5.24 ± 5.68 7.05 ± 7.82 6.31 ± 5.33
EOS (%) 1.04 ± 0.46 0.90 ± 0.21 1.08 ± 0.73 0.91 ± 0.51 1.58 ± 1.83 1.34 ± 0.57
LUC (%) 4.36 ± 3.93 2.96 ± 3.35 3.73 ± 4.81 4.07 ± 5.04 4.33 ± 4.4 6.21 ± 6.14
BASO (%) 0.66 ± 0.32 0.43 ± 0.10 0.93 ± 0.79 0.61 ± 0.21 0.63 ± 0.18 0.89 ± 0.50
IgG (mg/mL) 2.57 ± 0.93 3.42 ± 0.93 2.77 ± 0.97 3.48 ± 1.71 5.48 ± 2.21# 2.89 ± 1.62
IgM (µg/mL) 108.2 ± 38.9 94.8 ± 21.9 84.1 ± 18.7 218.4 ± 303.5 107 ± 18.3 85.9 ± 29.8
IgA (µg/mL) 22.7 ± 3.4 24.7 ± 2.6 24.9 ± 12.0 18.7 ± 2.7 38.2 ± 11.7 22.4 ± 3.2
IgE (ng/mL) 9.2 ± 9.1 14.5 ± 26.1 6.3 ± 6.1 240.3 ± 263.6* 410.1 ± 266.7* 115.9 ± 199.3*
  1. Mean ± SD of 6–7 animals per treatment group
  2. RBC: red blood cells; HGB: hemoglobin; HCT: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; PLT: platelet; MPV: mean platelet volume; WBC: white blood cells; LYM: lymphocytes; NEUT: neutrophils; MONO, monocytes; EOS: eosinophils; LUC: large unstained cells; BASO: basophils
  3. * Significantly different from control group values (P < 0.05) as assessed by one-way ANOVA followed by Dunnett post hoc test
  4. #Significantly different from control group values (P < 0.05) as assessed by Kruskal–Wallis ANOVA followed by Dunnett post hoc test on ranks