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Table 2 Effects of treatments on rat hematological parameters

From: Co-administration of a Rhododendron tomentosum extract does not affect mercury tissue concentrations and excretion rate in methylmercury-treated adult male rats

 

Control

Labrador Tea

Antibiotics

MeHg

MeHg + Labrador Tea

MeHg + antibiotics

RBC (× 106 cells/µL)

7.54 ± 0.46

7.59 ± 0.15

7.93 ± 0.32

7.83 ± 0.32

7.86 ± 0.29

7.75 ± 0.37

HGB (g/dL)

14.36 ± 0.49

14.11 ± 0.34

14.37 ± 0.43

14.39 ± 0.29

14.37 ± 0.61

14.33 ± 0.54

HCT (%)

42.31 ± 1.95

42.01 ± 1.50

43.50 ± 1.08

43.84 ± 1.35

43.67 ± 1.92

43.57 ± 1.82

MCV (fL)

56.20 ± 1.10

55.36 ± 1.18

54.95 ± 1.42

56.03 ± 1.77

55.53 ± 1.69

56.24 ± 2.00

MCH (pg)

19.07 ± 0.70

18.59 ± 0.31

18.18 ± 0.43

18.4 ± 0.59

18.28 ± 0.48

18.46 ± 0.59

MCHC (g/dL)

33.94 ± 0.72

33.59 ± 0.54

33.03 ± 0.64*

32.83 ± 0.63*

32.88 ± 0.58*

32.86 ± 0.32*

PLT (× 103 cells/µL)

867 ± 138

1010 ± 68*

921 ± 84

977 ± 45

969 ± 62

875 ± 159

MPV (fL)

6.03 ± 1.29

6.04 ± 1.11

6.08 ± 1.34

6.20 ± 1.08

6.40 ± 1.38

6.20 ± 1.37

WBC (× 103 cells/µL)

4.25 ± 1.57

4.62 ± 0.39

3.86 ± 1.50

5.79 ± 1.72

5.13 ± 1.4

4.24 ± 1.10

LYM (× 103 cells/µL)

3.21 ± 1.63

3.79 ± 0.37

3.26 ± 1.47

4.35 ± 1.53

3.92 ± 1.25

3.32 ± 0.75

NEUT (× 103 cells/µL)

0.57 ± 0.46

0.41 ± 0.25

0.30 ± 0.19

0.78 ± 0.90

0.5 ± 0.36

0.23 ± 0.16

MONO (× 103 cells/µL)

0.23 ± 0.22

0.22 ± 0.31

0.12 ± 0.12

0.32 ± 0.37

0.36 ± 0.39

0.29 ± 0.29

EOS (× 103 cells/µL)

0.041 ± 0.018

0.040 ± 0.008

0.040 ± 0.030

0.049 ± 0.020

0.073 ± 0.077

0.053 ± 0.027

LUC (× 103 cells/µL)

0.17 ± 0.14

0.14 ± 0.17

0.12 ± 0.12

0.25 ± 0.32

0.23 ± 0.25

0.30 ± 0.34

BASO (× 103 cells/µL)

0.03 ± 0.01

0.02 ± 0.00

0.03 ± 0.01

0.04 ± 0.02

0.03 ± 0.01

0.03 ± 0.02

LYM (%)

73.26 ± 13.50

82.01 ± 5.09

82.28 ± 7.63

75.09 ± 12.07

76.03 ± 5.22

79.13 ± 7.07

NEUT (%)

14.56 ± 12.89

9.06 ± 5.73

8.33 ± 5.30

14.09 ± 14.28

10.42 ± 7.35

6.16 ± 4.49

MONO (%)

6.11 ± 6.35

4.64 ± 6.40

3.65 ± 4.75

5.24 ± 5.68

7.05 ± 7.82

6.31 ± 5.33

EOS (%)

1.04 ± 0.46

0.90 ± 0.21

1.08 ± 0.73

0.91 ± 0.51

1.58 ± 1.83

1.34 ± 0.57

LUC (%)

4.36 ± 3.93

2.96 ± 3.35

3.73 ± 4.81

4.07 ± 5.04

4.33 ± 4.4

6.21 ± 6.14

BASO (%)

0.66 ± 0.32

0.43 ± 0.10

0.93 ± 0.79

0.61 ± 0.21

0.63 ± 0.18

0.89 ± 0.50

IgG (mg/mL)

2.57 ± 0.93

3.42 ± 0.93

2.77 ± 0.97

3.48 ± 1.71

5.48 ± 2.21#

2.89 ± 1.62

IgM (µg/mL)

108.2 ± 38.9

94.8 ± 21.9

84.1 ± 18.7

218.4 ± 303.5

107 ± 18.3

85.9 ± 29.8

IgA (µg/mL)

22.7 ± 3.4

24.7 ± 2.6

24.9 ± 12.0

18.7 ± 2.7

38.2 ± 11.7

22.4 ± 3.2

IgE (ng/mL)

9.2 ± 9.1

14.5 ± 26.1

6.3 ± 6.1

240.3 ± 263.6*

410.1 ± 266.7*

115.9 ± 199.3*

  1. Mean ± SD of 6–7 animals per treatment group
  2. RBC: red blood cells; HGB: hemoglobin; HCT: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; PLT: platelet; MPV: mean platelet volume; WBC: white blood cells; LYM: lymphocytes; NEUT: neutrophils; MONO, monocytes; EOS: eosinophils; LUC: large unstained cells; BASO: basophils
  3. * Significantly different from control group values (P < 0.05) as assessed by one-way ANOVA followed by Dunnett post hoc test
  4. #Significantly different from control group values (P < 0.05) as assessed by Kruskal–Wallis ANOVA followed by Dunnett post hoc test on ranks
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BMC Research Notes

ISSN: 1756-0500

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