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Table 2 Univariate analysis for factors associated with uncontrolled hypertension among Thai adults with hypertension

From: Prevalence and associated factors of uncontrolled hypertension among hypertensive patients: a nation-wide survey in Thailand

Variables

Normotension

Uncontrolled HT

Crude

95% CI

p-value

n (%)

n (%)

Odds ratio

Gender

 Female

31,077 (76.1)

9757 (23.9)

1

  

 Male

18,468 (74.4)

6365 (25.6)

1.10

(1.06–1.14)

< 0.001

Age (years)

64.9 ± 11.4

60.7 ± 12.2

0.97

(0.97–0.97)

< 0.001

 20–29

48 (49.0)

50 (51.0)

1

  

 30–39

625 (58.0)

452 (42.0)

0.69

(0.46–1.05)

0.084

 40–49

4064 (63.7)

2319 (36.3)

0.55

(0.37–0.82)

0.003

 50–59

10,811 (66.4)

5465 (33.6)

0.49

(0.33–0.72)

< 0.001

 60–69

16,251 (81.4)

3715 (18.6)

0.22

(0.15–0.33)

< 0.001

 70–79

12,613 (81.3)

2898 (18.7)

0.22

(0.15–0.33)

< 0.001

 80–89

4697 (80.5)

1135 (19.5)

0.23

(0.16–0.35)

< 0.001

 ≥ 90

384 (84.2)

72 (15.8)

0.18

(0.11–0.29)

< 0.001

Region

 Northeast

11,813 (79.5)

3051 (20.5)

1

  

 Northern

13,717 (76.1)

4315 (23.9)

1.22

(1.16–1.28)

< 0.001

 Central

17,101 (74.0)

6003 (26.0)

1.36

(1.29–1.43)

< 0.001

 Southern

6914 (71.5)

2753 (28.5)

1.54

(1.45–1.64)

< 0.001

Hospital level

 First level

35,160 (77.2)

10,381 (22.8)

1

  

 Middle level

10,668 (71.0)

4362 (29.0)

1.39

(1.33–1.44)

< 0.001

 Standard/advance level

3717 (72.9)

1379 (27.1)

1.26

(1.18–1.34)

< 0.001

Healthcare coverage

 Universal coverage scheme

36,881 (75.7)

11,866 (24.3)

1

  

 Government officer

10,193 (77.3)

2988 (22.7)

0.91

(0.87–0.95)

< 0.001

 Social security scheme

1903 (64.9)

1028 (35.1)

1.68

(1.55–1.82)

< 0.001

 Others

568 (70.3)

240 (29.7)

1.31

(1.13–1.53)

< 0.001

Occupations

 Unemployed/retired

17,809 (79.4)

4629 (20.6)

1

  

 Agriculturist

2387 (71.3)

959 (28.7)

1.55

(1.43–1.68)

< 0.001

 Private business

17,266 (76.2)

5383 (23.8)

1.20

(1.15–1.25)

< 0.001

 Officer

2706 (70.8)

1114 (29.2)

1.58

(1.47–1.71)

< 0.001

 Others

9377 (69.9)

4037 (30.1)

1.66

(1.58–1.74)

< 0.001

Dyslipidemia

 No

18,345 (74.9)

6151 (25.1)

1

  

 Yes

31,200 (75.8)

9971 (24.2)

0.95

(0.92–0.99)

0.010

Diabetes mellitus

 No

43,311 (75.9)

13,728 (24.1)

1

  

 Yes

6234 (72.3)

2394 (27.7)

1.21

(1.15–1.28)

< 0.001

Gout

 No

45,755 (75.5)

14,829 (24.5)

1

  

 Yes

3790 (74.6)

1293 (25.4)

1.05

(0.99–1.12)

0.126

Smoking

 Never

38,552 (76.0)

12,181 (24.0)

1

  

 Ex-smoker

5801 (76.1)

1823 (23.9)

0.99

(0.94–1.05)

0.851

 Current smoker

2202 (72.6)

833 (27.4)

1.20

(1.10–1.30)

< 0.001

Duration of hypertension (years)

6.6 ± 4.1

6.4 ± 4.0

0.99

(0.98–0.99)

< 0.001

Waist circumference (cm)

85.8 ± 10.6

87.8 ± 11.1

1.02

(1.01–1.02)

< 0.001

BMI (kg/m2)

24.6 ± 4.5

25.9 ± 4.9

1.06

(1.06–1.06)

< 0.001

 < 25

27,156 (79.6)

6981 (20.4)

1

  

 25–29.99

15,227 (73.2)

5570 (26.8)

1.42

(1.37–1.48)

< 0.001

 30–34.99

4309 (67.5)

2077 (32.5)

1.88

(1.77–1.99)

< 0.001

 ≥ 35

1048 (59.9)

703 (40.1)

2.61

(2.36–2.88)

< 0.001

Biochemical measurements

 Serum uric acid (mg/dL)

6.1 ± 1.8

6.2 ± 1.9

1.04

(1.03–1.06)

< 0.001

 TC (mg/dL)

192.3 ± 43.1

198.1 ± 49.0

1.01

(1.00–1.01)

< 0.001

 TG (mg/dL)

148.8 ± 87.3

157.5 ± 94.6

1.01

(1.00–1.01)

< 0.001

 HDL (mg/dL)

50.7 ± 15.8

50.8 ± 15.2

1.01

(1.00–1.01)

0.467

 LDL (mg/dL)

114.0 ± 36.4

118.5 ± 38.1

1.01

(1.00–1.01)

< 0.001

Estimated GFR (mL/min/1.73 m2)

70.2 ± 23.2

73.7 ± 24.7

1.01

(1.00–1.01)

< 0.001

 ≥ 90

9732 (71.2)

3946 (28.8)

1

  

 60–89

19,314 (76.5)

5949 (23.5)

0.76

(0.73–0.80)

< 0.001

 30–59

12,974 (79.0)

3444 (21.0)

0.66

(0.62–0.69)

< 0.001

 15–29

1274 (77.3)

375 (22.7)

0.73

(0.64–0.82)

< 0.001

 < 15

511 (69.9)

220 (30.1)

1.06

(0.90–1.25)

0.469

Number of antihypertensive medications

 0

930 (83.8)

180 (16.2)

1

  

 1

20,717 (79.2)

5436 (20.8)

1.36

(1.15–1.60)

< 0.001

 2

20,148 (74.1)

7027 (25.9)

1.80

(1.53–2.12)

< 0.001

 ≥ 3

7750 (69.0)

3479 (31.0)

2.32

(1.97–2.73)

< 0.001

Drug classes (monotherapy)

 ARB

1953 (76.6)

595 (23.4)

1

  

 ACEI

5520 (77.1)

1644 (22.9)

0.98

(0.88–1.09)

0.678

 Anti-adrenergic

2060 (78.4)

566 (21.6)

0.90

(0.79–1.03)

0.121

 Diuretics

2697 (80.9)

635 (19.1)

0.77

(0.68–0.88)

< 0.001

 CCBs

8301 (81.2)

1921 (18.8)

0.76

(0.68–0.84)

< 0.001

  1. SD standard deviation, mmHg millimeter of mercury, SBP systolic blood pressure, DBP diastolic blood pressure, cm centimeter, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, HDL, high-density lipoprotein cholesterol, LDL low-density lipoprotein cholesterol, BMI body mass index, eGFR estimated glomerulus filtration rate, ARB angiotensin receptor blockers, ACEI angiotensin converting enzyme inhibitors; anti-adrenergic; alpha and beta blockers, CCBs, calcium channel blockers