Variables | Normotension | Uncontrolled HT | Crude | 95% CI | p-value |
---|---|---|---|---|---|
n (%) | n (%) | Odds ratio | |||
Gender | |||||
Female | 31,077 (76.1) | 9757 (23.9) | 1 | ||
Male | 18,468 (74.4) | 6365 (25.6) | 1.10 | (1.06–1.14) | < 0.001 |
Age (years) | 64.9 ± 11.4 | 60.7 ± 12.2 | 0.97 | (0.97–0.97) | < 0.001 |
20–29 | 48 (49.0) | 50 (51.0) | 1 | ||
30–39 | 625 (58.0) | 452 (42.0) | 0.69 | (0.46–1.05) | 0.084 |
40–49 | 4064 (63.7) | 2319 (36.3) | 0.55 | (0.37–0.82) | 0.003 |
50–59 | 10,811 (66.4) | 5465 (33.6) | 0.49 | (0.33–0.72) | < 0.001 |
60–69 | 16,251 (81.4) | 3715 (18.6) | 0.22 | (0.15–0.33) | < 0.001 |
70–79 | 12,613 (81.3) | 2898 (18.7) | 0.22 | (0.15–0.33) | < 0.001 |
80–89 | 4697 (80.5) | 1135 (19.5) | 0.23 | (0.16–0.35) | < 0.001 |
≥ 90 | 384 (84.2) | 72 (15.8) | 0.18 | (0.11–0.29) | < 0.001 |
Region | |||||
Northeast | 11,813 (79.5) | 3051 (20.5) | 1 | ||
Northern | 13,717 (76.1) | 4315 (23.9) | 1.22 | (1.16–1.28) | < 0.001 |
Central | 17,101 (74.0) | 6003 (26.0) | 1.36 | (1.29–1.43) | < 0.001 |
Southern | 6914 (71.5) | 2753 (28.5) | 1.54 | (1.45–1.64) | < 0.001 |
Hospital level | |||||
First level | 35,160 (77.2) | 10,381 (22.8) | 1 | ||
Middle level | 10,668 (71.0) | 4362 (29.0) | 1.39 | (1.33–1.44) | < 0.001 |
Standard/advance level | 3717 (72.9) | 1379 (27.1) | 1.26 | (1.18–1.34) | < 0.001 |
Healthcare coverage | |||||
Universal coverage scheme | 36,881 (75.7) | 11,866 (24.3) | 1 | ||
Government officer | 10,193 (77.3) | 2988 (22.7) | 0.91 | (0.87–0.95) | < 0.001 |
Social security scheme | 1903 (64.9) | 1028 (35.1) | 1.68 | (1.55–1.82) | < 0.001 |
Others | 568 (70.3) | 240 (29.7) | 1.31 | (1.13–1.53) | < 0.001 |
Occupations | |||||
Unemployed/retired | 17,809 (79.4) | 4629 (20.6) | 1 | ||
Agriculturist | 2387 (71.3) | 959 (28.7) | 1.55 | (1.43–1.68) | < 0.001 |
Private business | 17,266 (76.2) | 5383 (23.8) | 1.20 | (1.15–1.25) | < 0.001 |
Officer | 2706 (70.8) | 1114 (29.2) | 1.58 | (1.47–1.71) | < 0.001 |
Others | 9377 (69.9) | 4037 (30.1) | 1.66 | (1.58–1.74) | < 0.001 |
Dyslipidemia | |||||
No | 18,345 (74.9) | 6151 (25.1) | 1 | ||
Yes | 31,200 (75.8) | 9971 (24.2) | 0.95 | (0.92–0.99) | 0.010 |
Diabetes mellitus | |||||
No | 43,311 (75.9) | 13,728 (24.1) | 1 | ||
Yes | 6234 (72.3) | 2394 (27.7) | 1.21 | (1.15–1.28) | < 0.001 |
Gout | |||||
No | 45,755 (75.5) | 14,829 (24.5) | 1 | ||
Yes | 3790 (74.6) | 1293 (25.4) | 1.05 | (0.99–1.12) | 0.126 |
Smoking | |||||
Never | 38,552 (76.0) | 12,181 (24.0) | 1 | ||
Ex-smoker | 5801 (76.1) | 1823 (23.9) | 0.99 | (0.94–1.05) | 0.851 |
Current smoker | 2202 (72.6) | 833 (27.4) | 1.20 | (1.10–1.30) | < 0.001 |
Duration of hypertension (years) | 6.6 ± 4.1 | 6.4 ± 4.0 | 0.99 | (0.98–0.99) | < 0.001 |
Waist circumference (cm) | 85.8 ± 10.6 | 87.8 ± 11.1 | 1.02 | (1.01–1.02) | < 0.001 |
BMI (kg/m2) | 24.6 ± 4.5 | 25.9 ± 4.9 | 1.06 | (1.06–1.06) | < 0.001 |
< 25 | 27,156 (79.6) | 6981 (20.4) | 1 | ||
25–29.99 | 15,227 (73.2) | 5570 (26.8) | 1.42 | (1.37–1.48) | < 0.001 |
30–34.99 | 4309 (67.5) | 2077 (32.5) | 1.88 | (1.77–1.99) | < 0.001 |
≥ 35 | 1048 (59.9) | 703 (40.1) | 2.61 | (2.36–2.88) | < 0.001 |
Biochemical measurements | |||||
Serum uric acid (mg/dL) | 6.1 ± 1.8 | 6.2 ± 1.9 | 1.04 | (1.03–1.06) | < 0.001 |
TC (mg/dL) | 192.3 ± 43.1 | 198.1 ± 49.0 | 1.01 | (1.00–1.01) | < 0.001 |
TG (mg/dL) | 148.8 ± 87.3 | 157.5 ± 94.6 | 1.01 | (1.00–1.01) | < 0.001 |
HDL (mg/dL) | 50.7 ± 15.8 | 50.8 ± 15.2 | 1.01 | (1.00–1.01) | 0.467 |
LDL (mg/dL) | 114.0 ± 36.4 | 118.5 ± 38.1 | 1.01 | (1.00–1.01) | < 0.001 |
Estimated GFR (mL/min/1.73 m2) | 70.2 ± 23.2 | 73.7 ± 24.7 | 1.01 | (1.00–1.01) | < 0.001 |
≥ 90 | 9732 (71.2) | 3946 (28.8) | 1 | ||
60–89 | 19,314 (76.5) | 5949 (23.5) | 0.76 | (0.73–0.80) | < 0.001 |
30–59 | 12,974 (79.0) | 3444 (21.0) | 0.66 | (0.62–0.69) | < 0.001 |
15–29 | 1274 (77.3) | 375 (22.7) | 0.73 | (0.64–0.82) | < 0.001 |
< 15 | 511 (69.9) | 220 (30.1) | 1.06 | (0.90–1.25) | 0.469 |
Number of antihypertensive medications | |||||
0 | 930 (83.8) | 180 (16.2) | 1 | ||
1 | 20,717 (79.2) | 5436 (20.8) | 1.36 | (1.15–1.60) | < 0.001 |
2 | 20,148 (74.1) | 7027 (25.9) | 1.80 | (1.53–2.12) | < 0.001 |
≥ 3 | 7750 (69.0) | 3479 (31.0) | 2.32 | (1.97–2.73) | < 0.001 |
Drug classes (monotherapy) | |||||
ARB | 1953 (76.6) | 595 (23.4) | 1 | ||
ACEI | 5520 (77.1) | 1644 (22.9) | 0.98 | (0.88–1.09) | 0.678 |
Anti-adrenergic | 2060 (78.4) | 566 (21.6) | 0.90 | (0.79–1.03) | 0.121 |
Diuretics | 2697 (80.9) | 635 (19.1) | 0.77 | (0.68–0.88) | < 0.001 |
CCBs | 8301 (81.2) | 1921 (18.8) | 0.76 | (0.68–0.84) | < 0.001 |