Polymorphisms rs693421 and rs2499601 at locus 1q43 and their haplotypes are not associated with primary open-angle glaucoma: a case–control study

Table 3 Comparison of rs693421 and rs2499601 minor allele frequency distribution among different ethnic group

Population	SNP	Minor allele frequency^a		p value	References
Population	SNP	Controls	POAG	p value	References
Japan	rs693421	0.450	0.550	0.00029	[7]
Japan	rs2499601	0.460	0.550	0.00058	[7]
India	rs693421	0.357	0.405	0.616	[17]
India	rs2499601	0.413	0.482	0.286	[17]
Afro-Caribbean	rs693421	0.291	0.313	0.733	[18]
Afro-Caribbean	rs2499601	0.295	0.271	0.528	[18]
Korea	rs693421	0.476	0.548	0.030	[21]
Korea	rs2499601	0.480	0.533	0.120	[21]
Japan	rs693421	0.498	0.528	0.246	[19]
Japan	rs2499601	0.497	0.530	0.208	[19]
China	rs693421	0.465	0.459	0.98	[20]
China	rs2499601	ns	ns	–	[20]
Saudi	rs693421	0.482	0.516	0.368	This study
Saudi	rs2499601	0.485	0.530	0.236	This study