Table 1 Serum concentrations of select cytokines/chemokines at sacrifice
Cytokine/chemokine | 8WD (n = 9–12) | 8WD + C (n = 9–11) | 12WD (n = 7–9) | 12WD + C (n = 8–11) |
|---|---|---|---|---|
EGF (pg/mL) | 3.52 ± 3.04 | 5.63 ± 3.50 | 7.79 ± 13.71 | 6.33 ± 4.86 |
Eotaxin (pg/mL) | 43.2 ± 17.6 | 56.7 ± 24.6 | 41.6 ± 23.0 | 59.2 ± 36.2 |
G-CSF (pg/mL) | 98 ± 35 | 153 ± 87 | 100 ± 52 | 100 ± 43 |
IL-1α (pg/mL) | 289 ± 159 | 321 ± 257 | 275 ± 355 | 288 ± 203 |
IL-1β (pg/mL) | 133 ± 83 | 147 ± 94 | 107 ± 61 | 136 ± 84 |
IL-4 (pg/mL) | 132 ± 88 | 153 ± 109 | 92 ± 80 | 121 ± 66 |
IL-5 (pg/mL) | 363 ± 114 | 347 ± 101 | 324 ± 195 | 527 ± 308 |
IL-6 (ng/mL) | 1.46 ± 1.37 | 1.82 ± 1.46 | 0.64 ± 0.50 | 1.12 ± 0.88 |
IL-10 (pg/mL) | 109 ± 63 | 118 ± 91 | 85 ± 39 | 146 ± 125 |
IL-12p70 (pg/mL) | 808 ± 375 | 882 ± 466 | 599 ± 99 | 681 ± 145 |
IL-18 (pg/mL) | 342 ± 217 | 470 ± 293 | 340 ± 272 | 425 ± 255 |
IP-10 (pg/mL) | 296 ± 78 | 274 ± 56 | 369 ± 72 | 375 ± 80 |
Leptin (ng/mL) | 38.8 ± 21.6 | 51.4 ± 28.6 | 54.2 ± 27.5 | 50.0 ± 24.7 |
LIX (ng/mL) | 3.54 ± 0.89 | 3.18 ± 1.25 | 3.82 ± 0.60 | 4.00 ± 0.55 |
MCP-1 (ng/mL) | 1.75 ± 0.34 | 1.70 ± 0.57 | 1.48 ± 0.31 | 1.66 ± 0.39 |
MIP-1α (pg/mL) | 35.5 ± 11.3 | 38.5 ± 13.9 | 32.5 ± 6.1 | 39.9 ± 13.4 |
MIP-2 (pg/mL) | 112 ± 39 | 142 ± 38 | 101 ± 48 | 163 ± 139 |
TNFα (pg/mL) | 93 ± 50 | 103 ± 61 | 69 ± 27 | 94 ± 42 |
VEGF (pg/mL) | 63.1 ± 33.1 | 75.8 ± 34.6 | 61.4 ± 23.9 | 99.6 ± 61.0 |