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Table 1 Profile characteristics of infection (n = 125)

From: Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case–control study

Characteristics Age < 50 years, n = 65 (IQR*) Age ≥ 50 years, n = 60 (IQR*) P value
Years since diagnosis 1 (0.8–3.5) 7 (2–16) < 0.001
CD4+ cell count, cells/mm3 384 (262–562) 509 (324–730) 0.021
HIV log10 HIV RNA 1.27 (1.27–2.24) 1.27 (1.27–1.27) 0.003
HIV RNA viral load < 50 copies/mLa, number (%) 41 (63%) 48 (80%) 0.015
Total number of drugs used, ART plus non-ART 4 (3–5) 6 (4–8) < 0.001
Total number of ART drugs usedb 3 (3–4) 4 (3–4) 0.002
Total number of comorbidities found 2 (1–3) 3.5 (2–5) < 0.001
BMI, kg/m2 23.75 (21.61–26.05) 25.52 (22.96–28.51) 0.018
Accumulated exposure/smoking index 0.1 (0–0.75) 0.1 (0–9.7) < 0.001
  1. *Data are presented as the median (IQR) unless indicated otherwise
  2. aPer log10 copies/mL increase (centered at 1.30, level of detection)
  3. bOnly patients with current ART (9 younger patients did not have medically indicated treatment)
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