Skip to main content

Table 2 Multivariable linear regression with pain intensity at rest 5 years as dependent variable

From: Persistent lumbar radicular and low back pain; impact of genetic variability versus emotional distress

  Unstandardized coefficients Confidence interval Sig.
B SE Lower Upper
a)
 MMP9 0.68 0.25 0.18 1.18 0.008
  Age 0.04 0.02 − 0.00 0.07 0.053
  Gender − 0.00 0.35 − 0.70 0.698 1.000
  Smoking 0.25 0.37 − 0.48 0.97 0.856
  BMI 0.01 0.03 − 0.05 0.07 0.856
  Pain (VAS) rest baseline 0.34 0.08 0.19 0.49 < 0.001
  Pain location (LRP or LBP) 0.79 0.36 0.09 1.49 0.027
  Emotional distress (HSCL-10) baseline 0.74 0.32 0.10 1.38 0.023
  R2      0.26
  Adjusted R2      0.23
b)
 OPRM1 − 0.72 0.38 − 1.46 0.02 0.058
  Age 0.03 0.02 − 0.01 0.07 0.089
  Gender − 0.19 0.35 − 0.89 0.51 0.586
  Smoking 0.33 0.37 − 0.40 1.06 0.367
  BMI 0.01 0.03 − 0.05 0.07 0.742
  Pain (VAS) rest baseline 0.34 0.08 0.19 0.49 < 0.001
  Pain location (LRP or LBP) 0.88 0.36 0.18 1.59 0.014
  Emotional distress (HSCL-10) baseline 0.64 0.33 − 0.01 1.28 0.052
  R2      0.25
  Adjusted R2      0.21
  1. Multivariable linear regression with pain intensity (VAS) at rest at 5 years as dependent variable. a) MMP9 as predictor adjusted for demographic and clinical confounders and controlled for emotional distress. b) OPRM1 as predictor adjusted for demographic and clinical confounders and controlled for emotional distress