Risk factors for mortality of patients with ceftriaxone resistant E. coli bacteremia receiving carbapenem versus beta lactam/beta lactamase inhibitor therapy

Table 1 Comparison of demographics and clinical features of patients with ceftriaxone resistant E. coli bacteremia who died compared to those who survived

Patient characteristics	Died (n = 62)	Recovered (n = 235)	p-value
Age (mean ± SD)	55.28 ± 17.87	60.14 ± 16.46	0.046
Gender
Male	34	106	0.172
Female	28	129
Charlson comorbidity index (CCI), mean (SD)	2.98 (2.12)	1.93 (1.73)	< 0.001
Pitt bacteremia score, median (IQR)	3 (4)	1 (2)	< 0.001
Site of infection
Intra-abdominal	24	44	< 0.001
UTI	24	171
CLABSI	4	4
Gut translocation	4	5
Source unclear	6	11
Empirical antibiotics^a			0.012
Carbapenem	20	33
BL/BLI	31	121
Definitive antibiotics^b
Carbapenem	36	138	0.152
BL/BLI	12	77
Length of stay (mean ± SD)	11.27 ± 12.46	6.82 ± 5.68	< 0.001

^aEmpirical group includes only those patients who had been given either a carbapenem or BL/BLI combination treatment empirically
^bDefinitive group includes only those patients who had been given either a carbapenem or BL/BLI combination treatment as definitive treatment

ISSN: 1756-0500