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Fig. 1 | BMC Research Notes

Fig. 1

From: Mycobacterium indicus pranii therapy induces tumor regression in MyD88- and TLR2-dependent manner

Fig. 1

Antitumor efficacy of MIP is lost in MyD88−/− mice. Tumors were implanted in the right flank of wild-type and MyD88−/− mice by injecting B16F10 melanoma cells. Animals were treated with MIP or injected with PBS (control group) using treatment schedule depicted in a. Tumor dimensions were measured using Bernier’s caliper and tumor volume were calculated. MIP induced significant tumor regression in wild-type mice, but not in MyD88−/− animals (b). Data shown are the mean ± SEM of one of two independent experiments. *p < 0.05; ns not significant; n = 6

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