Liver enzyme elevation in patients taking HAART compared with treatment naïve controls at Debre Berhan Referral Hospital: a comparative cross-sectional study, Northeast Ethiopia

Table 2 Independent T-test of mean and 95% CI for mean level of liver enzymes of study participant at Debre Behan Referral Hospital, Northeast Ethiopia

Parameter	Study group	Number	Mean	95% CI for mean	p-value
ALT (U/L)	ART group	76	35.67	32.18–39.16	0.000*
ALT (U/L)	Pre-ART group	76	23.97	21.38-26.57	0.000*
AST (U/L)	ART group	76	36.05	32.88–39.23	0.000*
AST (U/L)	Pre-ART group	76	28.00	25.52–30.49	0.000*
ALP (U/L)	ART group	76	117.14	97.99–136.30	0.022*
ALP (U/L)	Pre-ART group	76	89.45	75.27–103.64	0.022*
Total protein (g/dL)	ART group	76	7.09	6.89–7.30	0.007*
Total protein (g/dL)	Pre-ART group	76	7.46	7.29–7.64	0.007*
Total bilirubin (mg/dL)	ART group	76	0.787	0.761–0.813	0.000*
Total bilirubin (mg/dL)	Pre-ART group	76	0.660	0.649–0.673	0.000*
Direct bilirubin (mg/dL)	ART group	76	0.275	0.227–0.324	0.007*
Direct bilirubin (mg/dL)	Pre-ART group	76	0.188	0.149–0.228	0.007*
Urea (mg/dL)	ART group	76	19.945	18.414–21.477	0.875
Urea (mg/dL)	Pre-ART group	76	19.750	17.824–21.678	0.875
Creatinine (mg/dL)	ART group	76	0.588	0.562–0.614	0.016*
Creatinine (mg/dL)	Pre-ART group	76	0.641	0.607–0.675	0.016*
Hemoglobin (g/dL)	Treatment group	76	15.44	14.98–15.91	0.245
Hemoglobin (g/dL)	Pre-ART group	76	15.02	14.46–15.58	0.245
CD4 count (cells/µL)	ART group	76	428.14	367.75–488.53	0.362
CD4 count (cells/µL)	Pre-ART group	76	390.97	336.93–445.01	0.362

ISSN: 1756-0500