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Table 2 Top variants from meta-analysis lookup in humanin-like nuclear isoform gene regions and with 50 kb flanking region in both directions

From: Genetic variants in humanin nuclear isoform gene regions show no association with coronary artery disease

Gene

Top SNP (with flanking)

Allelesa

EAF

OR

P-value

Top SNP (no flanking)

Alleles

EAF

OR (95% CI)

P-value

(95% CI)

MTRNR2L1

rs56173058

G/A

0.98

1.08 (1.01–1.16)

0.034

rs79253571

C/T

0.98

1.04 (0.98–1.11)

0.17

MTRNR2L2

rs6151662

G/A

0.95

1.06 (1.02–1.11)

0.0037

rs150977859

T/C

0.053

1.02 (0.98–1.06)

0.3

MTRNR2L3

rs117764606

T/C

0.014

1.11 (1.03–1.20)

0.0074

rs113906620

T/C

0.025

1.04 (0.99–1.10)

0.14

MTRNR2L4

rs75856110

T/C

0.0026

1.34 (1.08–1.67)

0.0086

rs72776357

C/A

0.88

1.01 (0.98–1.03)

0.48

MTRNR2L5

rs72788864

G/A

0.05

1.05 (1.01–1.10)

0.016

rs11004929

C/T

0.37

1.01 (1.00–1.03)

0.1

MTRNR2L6

rs34587783

T/C

0.93

1.04 (1.01–1.08)

0.0087

rs58504986

A/G

0.56

1.01 (1.00–1.03)

0.14

MTRNR2L7

rs148910803

C/G

0.99

1.12 (1.00–1.24)

0.047

rs2208320

G/T

0.34

1.01 (0.99–1.02)

0.55

MTRNR2L8

rs76836360

T/C

0.00016

3.52 (1.48–8.37)

0.0044

rs7350542

G/A

0.19

1.02 (0.99–1.04)

0.15

MTRNR2L9

rs60678216

G/A

0.035

1.05 (1.01–1.10)

0.026

rs6915206

C/T

0.4

1 (0.99–1.02)

0.59

MTRNR2L10

rs5914251

C/A

0.14

1.02 (0.99–1.05)

0.15

rs10521478

A/G

0.57

1.01 (0.98–1.04)

0.62

MTRNR2L11

rs202137689

TG/-

0.03

1.06 (1.01–1.11)

0.029

rs12093187

C/T

0.029

1.04 (0.98–1.10)

0.25

MTRNR2L12

rs78077066

T/G

0.01

1.12 (1.02–1.23)

0.015

rs12106821

A/G

0.037

1.02 (0.95–1.10)

0.52

MTRNR2L13

rs10020248

C/T

0.21

1.03 (1.01–1.05)

0.013

rs78083998

G/C

0.031

1.05 (1.10–1.00)

0.042

  1. aEffect allele/other allele