TY - JOUR AU - Pandey, Priyatama AU - Yang, Zhi AU - Shibata, Darryl AU - Marjoram, Paul AU - Siegmund, Kimberly D. PY - 2019 DA - 2019/12/03 TI - Mutational signatures in colon cancer JO - BMC Research Notes SP - 788 VL - 12 IS - 1 AB - Recently, many tumor sequencing studies have inferred and reported on mutational signatures, short nucleotide patterns at which particular somatic base substitutions appear more often. A number of signatures reflect biological processes in the patient and factors associated with cancer risk. Our goal is to infer mutational signatures appearing in colon cancer, a cancer for which environmental risk factors vary by cancer subtype, and compare the signatures to those in adult stem cells from normal colon. We also compare the mutational signatures to others in the literature. SN - 1756-0500 UR - https://doi.org/10.1186/s13104-019-4820-0 DO - 10.1186/s13104-019-4820-0 ID - Pandey2019 ER -