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Table 1 Clinical and biochemical characteristics of 30-day survivor and non-survivor trauma brain injury patients

From: Maintained high sustained serum malondialdehyde levels after severe brain trauma injury in non-survivor patients

 

Non-survivors (n = 34)

Survivors (n = 90)

p Value

Computer tomography classification—n (%)

  

0.01

 Type 1

0

0

 

 Type 2

5 (14.7)

25 (27.8)

 

 Type 3

6 (17.6)

15 (16.7)

 

 Type 4

9 (26.5)

13 (14.4)

 

 Type 5

6 (17.6)

32 (35.6)

 

 Type 6

8 (23.5)

5 (5.6)

 

CT with high risk of death (types 3, 4, 6)—n (%)

23 (67.6)

33 (36.7)

0.002

Gender female—n (%)

13 (38.2)

15 (16.7)

0.02

Age (years)—median (p 25–75)

65 (55–75)

46 (28–62)

< 0.001

Temperature (°C)—median (p 25–75)

36.0 (35.0–37.0)

37.0 (36.0–37.3)

0.07

Creatinine (mg/dl)—median (p 25–75)

0.80 (0.70–1.10)

0.80 (0.70–1.00)

0.50

Glycemia (g/dL)—median (p 25–75)

160 (125–191)

139 (121–167)

0.11

Sodium (mEq/L)—median (p 25–75)

141 (136–147)

140 (138–143)

0.41

Bilirubin (mg/dl)—median (p 25–75)

0.70 (0.53–1.05)

0.60 (0.40–0.80)

0.06

Lactic acid (mmol/L) median (p 25–75)

2.30 (1.25–4.58)

1.75 (1.10–2.50)

0.08

PaO2 (mmHg)—median (p 25–75)

142 (97–195)

148 (110–242)

0.45

PaO2/FI02 ratio—median (p 25–75)

294 (167–395)

336 (246–400)

0.11

Leukocytes—median*103/mm3 (p 25–75)

14.9 (9.7–21.6)

13.9 (10.1–19.0)

0.47

Fibrinogen (mg/dl)—median (p 25–75)

348 (300–475)

371 (286–471)

0.70

aPTT (seconds)—median (p 25–75)

29 (25–37)

28 (25–31)

0.25

INR—median (p 25–75)

1.12 (1.03–1.48)

1.11 (1.00–1.24)

0.19

Platelets—median*103/mm3 (p 25–75)

172 (125–232)

182 (135–238)

0.49

Hemoglobin (g/dL)—median (p 25–75)

11.9 (10.0–13.7)

11.2 (10.0–13.0)

0.73

ISS—median (ppe 25–75)

25 (25–25)

25 (25–34)

0.28

Glasgow Coma Scale score—median (p 25–75)

4 (3–7)

7 (5–8)

< 0.001

APACHE–II score—median (p 25–75)

25 (23–28)

18 (14–22)

< 0.001

ICP (mmHg)—median (p 25–75)

25 (11–30)

15 (14–20)

0.36

CPP (mmHg)—median (p 25–75)

61 (52–70)

68 (57–70)

0.60

Malondialdehyde (nmol/mL)—median (p 25–75)

2.03 (1.36–4.12)

1.35 (1.05–1.77)

< 0.001

  1. PaO2 pressure of arterial oxygen/fraction inspired oxygen, FIO2 pressure of arterial oxygen/fraction inspired oxygen, aPTT activated partial thromboplastin time, INR international normalized ratio, ISS Injury Severity Score, GCS Glasgow Coma Scale, APACHE II Acute Physiology and Chronic Health Evaluation, ICP intracranial pressure, CPP cerebral perfusion pressure, p 25–75 percentile 25th–75th