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Table 1 Clinical and biochemical characteristics of 30-day survivor and non-survivor trauma brain injury patients

From: Maintained high sustained serum malondialdehyde levels after severe brain trauma injury in non-survivor patients

 Non-survivors (n = 34)Survivors (n = 90)p Value
Computer tomography classification—n (%)  0.01
 Type 100 
 Type 25 (14.7)25 (27.8) 
 Type 36 (17.6)15 (16.7) 
 Type 49 (26.5)13 (14.4) 
 Type 56 (17.6)32 (35.6) 
 Type 68 (23.5)5 (5.6) 
CT with high risk of death (types 3, 4, 6)—n (%)23 (67.6)33 (36.7)0.002
Gender female—n (%)13 (38.2)15 (16.7)0.02
Age (years)—median (p 25–75)65 (55–75)46 (28–62)< 0.001
Temperature (°C)—median (p 25–75)36.0 (35.0–37.0)37.0 (36.0–37.3)0.07
Creatinine (mg/dl)—median (p 25–75)0.80 (0.70–1.10)0.80 (0.70–1.00)0.50
Glycemia (g/dL)—median (p 25–75)160 (125–191)139 (121–167)0.11
Sodium (mEq/L)—median (p 25–75)141 (136–147)140 (138–143)0.41
Bilirubin (mg/dl)—median (p 25–75)0.70 (0.53–1.05)0.60 (0.40–0.80)0.06
Lactic acid (mmol/L) median (p 25–75)2.30 (1.25–4.58)1.75 (1.10–2.50)0.08
PaO2 (mmHg)—median (p 25–75)142 (97–195)148 (110–242)0.45
PaO2/FI02 ratio—median (p 25–75)294 (167–395)336 (246–400)0.11
Leukocytes—median*103/mm3 (p 25–75)14.9 (9.7–21.6)13.9 (10.1–19.0)0.47
Fibrinogen (mg/dl)—median (p 25–75)348 (300–475)371 (286–471)0.70
aPTT (seconds)—median (p 25–75)29 (25–37)28 (25–31)0.25
INR—median (p 25–75)1.12 (1.03–1.48)1.11 (1.00–1.24)0.19
Platelets—median*103/mm3 (p 25–75)172 (125–232)182 (135–238)0.49
Hemoglobin (g/dL)—median (p 25–75)11.9 (10.0–13.7)11.2 (10.0–13.0)0.73
ISS—median (ppe 25–75)25 (25–25)25 (25–34)0.28
Glasgow Coma Scale score—median (p 25–75)4 (3–7)7 (5–8)< 0.001
APACHE–II score—median (p 25–75)25 (23–28)18 (14–22)< 0.001
ICP (mmHg)—median (p 25–75)25 (11–30)15 (14–20)0.36
CPP (mmHg)—median (p 25–75)61 (52–70)68 (57–70)0.60
Malondialdehyde (nmol/mL)—median (p 25–75)2.03 (1.36–4.12)1.35 (1.05–1.77)< 0.001
  1. PaO2 pressure of arterial oxygen/fraction inspired oxygen, FIO2 pressure of arterial oxygen/fraction inspired oxygen, aPTT activated partial thromboplastin time, INR international normalized ratio, ISS Injury Severity Score, GCS Glasgow Coma Scale, APACHE II Acute Physiology and Chronic Health Evaluation, ICP intracranial pressure, CPP cerebral perfusion pressure, p 25–75 percentile 25th–75th