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Table 2 Receiver operation characteristic analysis using serum malondialdehyde levels at day 1, 4 and 8 of trauma brain injury as predictor of mortality at 30 days

From: Maintained high sustained serum malondialdehyde levels after severe brain trauma injury in non-survivor patients

 Day 1Day 4Day 8
Cut-off of malondialdehyde (mmol/mL)> 1.96> 1.83> 1.83
AUC, 95% CI, and p value0.77 (0.68–0.84)
p < 0.001
0.87 (0.79–0.93)
p < 0.001
0.84 (0.75–0.90)
p < 0.001
Sensitivity and 95% CI56% (38%–73%)77% (50%–93%)85% (55%–98%)
Specificity and 95% CI84% (75%–91%)92% (85%–97%)86% (77%–92%)
Positive likelihood ratio and 95% CI3.6 (2.0–6.3)9.8 (4.6–21.8)5.9 (3.4–10.2)
Negative likelihood ratio and 95% CI0.5 (0.4–0.8)0.4 (0.2–0.7)0.2 (0.1–0.6)
Positive predicted value and 95% CI58% (44%–71%)65% (44%–81%)46% (33%–60%)
Negative predicted value and 95% CI84% (78%–88%)93% (88%–96%)98% (92%–99%)
  1. AUC area under curve, CI confidence intervals
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