Table 2 Receiver operation characteristic analysis using serum malondialdehyde levels at day 1, 4 and 8 of trauma brain injury as predictor of mortality at 30 days
Day 1 | Day 4 | Day 8 | |
|---|---|---|---|
Cut-off of malondialdehyde (mmol/mL) | > 1.96 | > 1.83 | > 1.83 |
AUC, 95% CI, and p value | 0.77 (0.68–0.84) p < 0.001 | 0.87 (0.79–0.93) p < 0.001 | 0.84 (0.75–0.90) p < 0.001 |
Sensitivity and 95% CI | 56% (38%–73%) | 77% (50%–93%) | 85% (55%–98%) |
Specificity and 95% CI | 84% (75%–91%) | 92% (85%–97%) | 86% (77%–92%) |
Positive likelihood ratio and 95% CI | 3.6 (2.0–6.3) | 9.8 (4.6–21.8) | 5.9 (3.4–10.2) |
Negative likelihood ratio and 95% CI | 0.5 (0.4–0.8) | 0.4 (0.2–0.7) | 0.2 (0.1–0.6) |
Positive predicted value and 95% CI | 58% (44%–71%) | 65% (44%–81%) | 46% (33%–60%) |
Negative predicted value and 95% CI | 84% (78%–88%) | 93% (88%–96%) | 98% (92%–99%) |