Skip to main content

Table 2 Biochemical profile of the study participants

From: Evaluation of serum iron overload, AST:ALT ratio and log10ferritin:AST ratio among schizophrenia patients in the Kumasi Metropolis, Ghana: a case–control study

VariablesTotal (n = 200)Control (N = 50)T (n = 75)p-valueTN (N = 75)#p-value
Markers of iron overload
 Serum iron (µmol/l)37.2 ± 1.131.3 ± 1.833.5 ± 1.40.351944.9 ± 1.8< 0.0001
 Serum UIBC (µmol/l)60.9 ± 1.669.6 ± 2.166.2 ± 2.50.284640.0 ± 2.5< 0.0001
 Serum TIBC (µmol/l)95.2 ± 2.4100.9 ± 3.799.6 ± 3.40.537484.9 ± 3.1< 0.0001
 Serum ferritin (ng/ml)92.1 ± 5.181.6 ± 7.594.3 ± 8.20.282797.0 ± 10.90.2956
 log10 (ferritin)1.8 ± 0.01.8 ± 0.11.9 ± 0.00.56741.9 ± 0.00.3975
 Serum transferrin (g/l)3.8 ± 0.14.02 ± 0.13.9 ± 0.10.37613.4 ± 0.1< 0.0001
 % transferrin saturation39.2 ± 0.831.01 ± 0.933.6 ± 1.00.314552.9 ± 1.6< 0.0001
Markers of liver function
 Serum AST (U/l)24.7 ± 0.920.9 ± 1.223.9 ± 1.20.077328.0 ± 1.80.0035
 Serum ALT (U/l)17.9 ± 0.617.8 ± 1.417.4 ± 0.80.824018.5 ± 1.10.6570
 GGT (U/l)29.3 ± 1.821.32 ± 1.329.7 ± 1.90.050336.98 ± 2.40.0418
 AST:ALT ratio1.5 ± 0.01.29 ± 0.01.50 ± 0.10.02821.61 ± 0.10.0004
 log10ferrtin:AST ratio0.087 ± 0.00.096 ± 0.00.084 ± 0.00.04480.080 ± 0.00.0113
  1. Values are presented as mean ± standard deviation (SD) and frequency (proportion) where appropriate
  2. UIBC unsaturated iron binding capacity, TIBC total iron binding capacity, AST aspartate aminotransferase, ALT alanine aminotransferase, T treatment, GGT gamma-glutamyl transferase, TN treatment naïve
  3. p-value (comparison between control and treatment)
  4. #p-value (comparison between control and treatment naïve)