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Table 3 The appropriateness of antimicrobial therapy according to survey year

From: A trend in prevalence of antimicrobial use and appropriateness of antimicrobial therapy in an acute care hospital from 2018 to 2019: repeated prevalence surveys in Japan

 August 2018 (n = 43)aAugust 2019 (n = 51)ap-valueb
Appropriatec26 (60.6)21 (41.2)0.06
Inappropriate17 (39.4)30 (58.8)0.06
Reasons for inappropriatenessd
 No infection7 (16.3)5 (9.8)0.35
 Inappropriate dose or timing9 (20.9)6 (11.8)0.14
 Inappropriate duration0 (0.0)2 (3.9)0.50
 Inappropriate choice0 (0.0)4 (7.8)0.25
 Inappropriate spectrume2 (4.7)19 (37.3)0.002
  1. aData are shown as numbers (percentages)
  2. bComparison between the 2018 survey and the 2019 survey was performed using Fisher’s exact test
  3. cThe appropriateness of antimicrobial therapy was determined by members of the infection control team of each hospital based on the results of microbial tests at the time of the survey, antibiograms of each hospital, and the Infectious Diseases Society of America Practical Guidelines
  4. dOne antimicrobial drug could be given for more than one reason
  5. eAntimicrobial therapy was judged to be inappropriate if there were alternative antimicrobial drugs that were equally effective and had narrower spectrum activity