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Table 1 The characteristics, clinical features, and laboratory findings of the study population

From: Reduced serum BDNF levels are associated with the increased risk for developing MDD: a case–control study with or without antidepressant therapy

ParameterControls (n = 82)All patients (n = 85)Drug-naive patients (n = 41)Drug-treated patients (n = 44)pa valuepb valuepc valuepd value
Age in years31.13 ± 1.8233.37 ± 1.1034.13 ± 1.5032.64 ± 1.630.3000.2070.5450.504
Gender (F/M)50/3248/3726/1531/130.5720.7320.8510.635
BMI (kg/m2)24.83 ± 0.7526.60 ± 0.6525.18 ± 0.9027.97 ± 0.870.1370.7790.1120.142
Ham-D score4.96 ± 0.5519.96 ± 0.2923.90 ± 0.4211.01 ± 0.430.000*0.000*0.000*0.008*
Serum BDNF (pg/mL)723.77 ± 78.36578.62 ± 44.65387.80 ± 70.44651.21 ± 69.240.0830.002*0.1050.009*
  1. Age, BMI, Ham-D score, and the value of BDNF are shown in mean ± SEM. F/M, female/male; BMI, body mass index; Ham-D, 17-item Hamilton depression rating scale; pa, comparisons between controls and all patients; pb, comparisons between controls and non-treated patients; pc, comparisons between controls and treated patients; pd, comparisons between non-treated and treated patients
  2. *P < 0.05 (Significant difference between patient and control groups at 95% confidence interval)