Dietary total antioxidant capacity significantly interacts with 6-P21 rs2010963 gene polymorphisms in terms of cardio-metabolic risk factors in patients with metabolic syndrome

Table 2 The comparison of metabolic profile among participants according to median TAC score

Variable	TAC score	N	Mean	SD	P value
Age (year)	< median	127	44.21	9.40	0.04
Age (year)	≥ median	127	41.43	10.48	0.04
Male (%)	< median	127	70		0.031
Male (%)	≥ median	127	65.3		0.031
BMI (kg/m²)	< median	127	29.71	4.184	0.32
BMI (kg/m²)	≥ median	127	30.46	4.96	0.32
FBS (mg/dl)	< median	127	88.41	12.87	0.12
FBS (mg/dl)	≥ median	127	91.36	13.16	0.12
TC (mg/dl)	< median	127	192.61	36.20	0.53
TC (mg/dl)	≥ median	127	196.14	39.40	0.53
TG (mg/dl)	< median	127	180.58	101.87	0.82
TG (mg/dl)	≥median	127	176.88	108.80	0.82
HDL (mg/dl)	< median	127	43.22	10.96	0.76
HDL (mg/dl)	≥ median	127	42.76	9.93	0.76
LDL (mg/dl)	< median	127	122.34	28.41	0.16
LDL (mg/dl)	≥ median	127	128.69	33.66	0.16
ALT (IU/l)	< median	127	29.03	8.63	0.049
ALT (IU/l)	≥ median	127	25.07	8.53	0.049
AST (IU/l)	< median	127	32.21	10.48	0.021
AST (IU/l)	≥ median	127	27.44	10.29	0.021
BMI (kg/m²)	< median	127	29.71	4.184	0.32
BMI (kg/m²)	≥ median	127	30.46	4.96	0.32
SBP (mmHg)	< median	127	130.84	10.21	0.34
SBP (mmHg)	≥ median	127	132.47	10.71	0.34
DBP (mmHg)	< median	127	88.36	5.73	0.94
DBP (mmHg)	≥ median	127	88.29	7.13	0.94
MMP3 (ng/ml)	< median	127	4.46	3.42	0.96
MMP3 (ng/ml)	≥ median	127	4.42	3.45	0.96
Insulin (µIU/l)	< median	127	18.34	27.12	0.83
Insulin (µIU/l)	≥ median	127	17.05	19.52	0.83
Adiponectin	< median	127	13.81	4.16	0.76
Adiponectin	≥ median	127	14.11	4.95	0.76
HOMR-IR	< median	127	4.00	5.81	0.88
HOMR-IR	≥ median	127	3.79	4.50	0.88
QUICKI	< median	127	0.33	0.050	0.77
QUICKI	≥ median	127	0.34	0.053	0.77

Italic signifies P < 0.05
BMI body mass index, WC waist circumference, WHR waist to hip ratio, FBS fasting blood sugar, TC total cholesterol TG triglyceride, HDL high density lipoprotein cholesterol, LDL low density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase, SBP systolic blood pressure, DBP diastolic blood pressure, MMP-3 matrix metalloproteinase-3, HOMA-IR homeostatic model assessment of insulin resistance, QUICKI Quantitative Insulin Sensitivity Check Index
P value based on independent T-test using equal variable. Continuous variables data are presented based on mean (SD) (the P values for biochemical variables were obtained by ANCOVA adjusted for BMI, age and gender)

ISSN: 1756-0500