Table 1 Participant characteristics
Demographic characteristics | DS-TB (n = 155) N (%) | DR-TBa (n = 117) N (%) | p-value |
|---|---|---|---|
Age (years) | 0.783 | ||
≤ 30 | 82 (55.0) | 62 (53.5) | |
31–45 | 50 (33.6) | 43 (37.1) | |
≥ 46 | 18 (11.4) | 11 (9.5) | |
Sex | 0.355 | ||
Male | 103 (66.7) | 72 (62.2) | |
Female | 52 (33.3) | 45 (38.8) | |
HIV status | 0.404 | ||
Positive | 85 (54.8) | 69 (59.0) | |
Negative | 70 (45.2) | 48 (41.0) | |
HIV treatment | < 0.001 | ||
ART naïve | 38 (47.5) | 4 (6.1) | |
TDF-based regimens | 27 (33.8) | 40 (60.6) | |
Other regimens | 15 (18.8) | 22 (33.3) | |
TB treatment history | < 0.001 | ||
Category 1 | 117 (94.4) | 52 (70.3) | |
Category 2 | 7 (5.6) | 22 (29.7) | |
Current TB treatment duration | < 0.001 | ||
< 1 month | 102 (68) | 32 (28) | |
< 1 month | 49 (32) | 84 (72) | |
History of abdominal pain | 0.784 | ||
No | 64 (41.8) | 47 (41.9) | |
Yes | 89 (58.5) | 70 (58.1) | |
History of weight loss | < 0.001 | ||
No | 13 (8.5) | 30 (25.6) | |
Yes | 140 (91.5) | 87 (74.4) | |
Clinical characteristics | |||
Weight loss-prominent zygoma | 0.002 | ||
No | 42 (27.5) | 53 (45.3) | |
Yes | 111 (72.5) | 64 (54.7) | |
Weight loss-supraclavicular fossa | 0.010 | ||
No | 27 (17.7) | 36 (31.0) | |
Yes | 126 (82.3) | 80 (69.0) | |
Serum cortisol (nmol/L) | < 0.001 | ||
< 414 | 64 (42.1) | 97 (82.9) | |
> 414 | 88 (57.9) | 20 (17.1) | |
Sodium [Na] (mmol/L) | < 0.001 | ||
Low (< 135) | 43 (27.7) | 12 (10.3) | |
Normal (≥ 135) | 112 (72.3) | 105 (89.7) | |
Potassium [K] (mmol/L) | 0.043 | ||
≤ 5.0 | 125 (80.7) | 104 (89.7) | |
> 5.0 | 30 (19.3) | 12 (10.3) | |
Haemoglobin (g/dL) | < 0.001 | ||
≤ 9 | 46 (29.7) | 10 (8.6) | |
> 9 | 109 (70.3) | 106 (91.4) | |