Table 1 Clinical characteristics of the patient cohort. Results are expressed as mean ± 95% CI
From: Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease
Characteristic | NAFL (n = 10) | NASH F0-F2 (n = 10) | NASH F4 (n = 4) |
|---|---|---|---|
Age (years) | 39.8 ± 7.8 | 47.5 ± 8.9 | 66.8 ± 17.1 |
Gender (M %/F %) | 10/90 | 0/100 | 100/0 |
BMI (kg m−2) | 41.6 ± 6.5 | 42.7 ± 7.2 | 29.0 ± 11.2 |
Type 2 diabetes (%) | 10 | 30 | 100 |
AST (U l−1) | 23.3 ± 4.2 | 32.6 ± 17.0 | 31.8 ± 21.5 |
ALT (U l−1) | 24.2 ± 5.4 | 39.4 ± 24.3 | 33.3 ± 11.7 |
GGT (U l−1) | 16.0 ± 4.2 | 51.5 ± 27.8 | 139.5 ± 142.6 |
Platelets (103 µl−1) | 274.5 ± 29.9 | 297.3 ± 64.1 | 133.8 ± 87.0 |
Hb (g dl−1) | 13.2 ± 0.6 | 13.5 ± 1.3 | 12.4 ± 3.4 |
HbA1c (%) | 5.6 ± 0.3 | 6.1 ± 1.2 | 6.2 ± 1.8 |
Total cholesterol (mg dl−1) | 186.8 ± 21.1 | 195.4 ± 40.0 | |
LDL (mg dl−1) | 94.2 ± 16.3 | 103.2 ± 21.0 | |
HDL (mg dl−1) | 66.3 ± 11.8 | 44.4 ± 13.0 | |
Triglycerides (mg dl−1) | 121.7 ± 26.7 | 219.9 ± 76.5 | |
Bilirubin (mg dl−1) | 0.4 ± 0.1 | 0.4 ± 0.1 | |
Fasting glucose (mg dl−1) | 98.2 ± 18.5 | 97.5 ± 9.6 | |
HOMA-IR | 4.4 ± 2.4 | 6.9 ± 2.9 | |
Iron (µg dl−1) | 76.6 ± 26.4 | 66.3 ± 19.0 | |
Transferrin (mg dl−1) | 2.9 ± 0.3 | 2.6 ± 0.7 | |
Ferritin (µg l−1) | 60.0 ± 38.6 | 155.1 ± 122.3 | |
Copper (µg dl−1) | 137.4 ± 38.4 | 117.3 ± 39.6 |