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Table 1 Clinical characteristics of the patient cohort. Results are expressed as mean ± 95% CI

From: Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease

CharacteristicNAFL (n = 10)NASH F0-F2 (n = 10)NASH F4 (n = 4)
Age (years)39.8 ± 7.847.5 ± 8.966.8 ± 17.1
Gender (M %/F %)10/900/100100/0
BMI (kg m−2)41.6 ± 6.542.7 ± 7.229.0 ± 11.2
Type 2 diabetes (%)1030100
AST (U l−1)23.3 ± 4.232.6 ± 17.031.8 ± 21.5
ALT (U l−1)24.2 ± 5.439.4 ± 24.333.3 ± 11.7
GGT (U l−1)16.0 ± 4.251.5 ± 27.8139.5 ± 142.6
Platelets (103 µl−1)274.5 ± 29.9297.3 ± 64.1133.8 ± 87.0
Hb (g dl−1)13.2 ± 0.613.5 ± 1.312.4 ± 3.4
HbA1c (%)5.6 ± 0.36.1 ± 1.26.2 ± 1.8
Total cholesterol (mg dl−1)186.8 ± 21.1195.4 ± 40.0 
LDL (mg dl−1)94.2 ± 16.3103.2 ± 21.0 
HDL (mg dl−1)66.3 ± 11.844.4 ± 13.0 
Triglycerides (mg dl−1)121.7 ± 26.7219.9 ± 76.5 
Bilirubin (mg dl−1)0.4 ± 0.10.4 ± 0.1 
Fasting glucose (mg dl−1)98.2 ± 18.597.5 ± 9.6 
HOMA-IR4.4 ± 2.46.9 ± 2.9 
Iron (µg dl−1)76.6 ± 26.466.3 ± 19.0 
Transferrin (mg dl−1)2.9 ± 0.32.6 ± 0.7 
Ferritin (µg l−1)60.0 ± 38.6155.1 ± 122.3 
Copper (µg dl−1)137.4 ± 38.4117.3 ± 39.6 
Control population
REFAge, yearsGender (M%/F%)n
[11]43.8 ± 8.50/10010
[12]23–48100/05
[13]51.57 ± 6.9100/07
  1. NAFL non-alcoholic fatty liver, NASH non-alcoholic steatohepatitis, BMI body mass index, AST aspartate aminotransferase, ALT alanine aminotransferase, GGT γ-glutamyltransferase, Hb Haemoglobin, HbA1c haemoglobin A1c, LDL low-density lipoprotein, HDL high-density lipoprotein, HOMA-IR Homeostasis Model Assessment Insulin Resistance